Evidence map›Paper›PMID 40448845›Full record

ReviewAbdominal radiology (New York)2025

Chemical exchange saturation transfer magnetic resonance imaging of the kidney: applications and challenges.

Lu Liu, Songlin Guo, Zhaoyu Xing, Xingtian Yu, Wenxia Mi, Jiule Ding, Jie Chen, Wei Xing, Liang Pan

Abstract readReview
In one paragraph

Review in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lu LiuDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Songlin GuoDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Zhaoyu XingDepartment of Urology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Xingtian YuDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Wenxia MiDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Jiule DingDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Jie ChenDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Wei XingDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China.
Liang PanDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China. plczyy@outlook.com.

Funding

Changzhou Science and Technology Program CJ20244015Changzhou Science and Technology Program CZ20230027National Natural Science Foundation of China 82001763National Natural Science Foundation of China 82171901National Natural Science Foundation of China 82302141Natural Science Research of Jiangsu Higher Education Institutions of China BK20241776
6 · The paper itself

Abstract

The kidney plays a crucial role in regulating the acid-base balance of the body. The development of kidney diseases is often accompanied by changes in the renal PH, protein, glucose, urea, and other metabolites. Chemical exchange saturation transfer (CEST) imaging is a new magnetic resonance imaging (MRI) technique based on the chemical exchange between solute and water protons. The potential of CEST imaging in renal metabolic imaging stems from its ability to provide image contrast based on specific molecular compositions at relevant millimolar physiological concentrations. In this article, we briefly introduce the fundamental principles of CEST imaging and its applications in various renal disorders, including acute kidney injury, chronic kidney disease, renal tumors, and renal allograft rejection. Finally, we discuss the challenges and prospects of CEST imaging in the field of kidney diseases.

Indexed as

Kidney DiseasesMagnetic Resonance ImagingContrast MediaHumansContrast MediaChemical exchange saturation transferKidney diseaseMagnetic resonance imagingNeoplasms

Identifiers

PMID40448845
PMCPMC12602669

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.