Evidence map›Paper›PMID 40448793›Full record

ArticleJournal of ultrasound2025

Can transabdominal shear wave elastography play a role in solving the dilemma of complex cystic and solid ovarian tumors by ultrasound?

Mennatallah Mohamed Hanafy, Mariam Rafaat, Hebatullah Mohammed Ibrahem, Fatma Mohamed Magdy Atta, Lamiaa Mohamed Bassam Hashem

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Article in Journal of ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mennatallah Mohamed HanafyDiagnostic and Interventional Radiology Department, Kasr Al-Ainy Faculty of Medicine, Cairo University, Giza, Egypt. drmennamhanafy@gmail.com.ORCID http://orcid.org/0000-0002-4479-264X
Mariam RafaatDiagnostic and Interventional Radiology Department, Kasr Al-Ainy Faculty of Medicine, Cairo University, Giza, Egypt.
Hebatullah Mohammed IbrahemMisr Scan, Nasr, Cairo, Egypt.
Fatma Mohamed Magdy AttaObstetric and Gynecology Department Faculty of Medicine, Cairo University, Cairo, Egypt.
Lamiaa Mohamed Bassam HashemDiagnostic and Interventional Radiology Department, Kasr Al-Ainy Faculty of Medicine, Cairo University, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to assess the role of shear wave elastography in better characterizing complex cystic and solid ovarian tumors in correlation with other ultrasound features and histopathology. MATERIALS AND

methodsThe study included 40 patients with 40 unilateral complex cystic or solid ovarian lesions with a mean age of 43.2 ± 13.27 (mean ± SD). All patients were subjected to history taking, tumor markers assessment, ultrasound with Doppler assessment giving an ORADS score, and shear wave elastography assessment. (qualitatively and quantitatively). Correlation was done with the final histopathology.

resultsAccording to the final histopathological results of the 40 lesions, 14 (35%) were benign, four were borderline (10%), and 22 (55%) were malignant. Ultrasound and Doppler assessments revealed a higher frequency of irregular margins and Doppler score 4 in borderline/malignant patients compared to benign patients. ORADS ultrasound scoring system of the examined lesions showed a statistically significantly higher frequency of ORADS 5 in the malignant group, with ORADS sensitivity, specificity, and Diagnostic accuracy of 96.2%, 57.1, and 82.5%, respectively. Elastographic color mapping scores and elastographic readings were higher in borderline/malignant patients compared to benign patients and it significantly correlated with the Doppler score, ORADS score, color mapping score, and tumor markers.

conclusionThe study detected significant associations between malignancy and higher tumor markers, marginal irregularity, higher Doppler, and higher ORADS scores. Shear wave elastography positively correlated with tumor markers, Doppler score, and ORADS score. This supports the utility of elastography in discriminating malignant from benign ovarian tumors.

Indexed as

Elasticity Imaging TechniquesOvarian CystsOvarian NeoplasmsAbdomenAdultDiagnosis, DifferentialFemaleHumansMiddle AgedOvarySensitivity and SpecificityComplex cystic and solid ovarian tumorsDopplerORADSShear wave elastographyTumor markersUltrasound

Identifiers

PMID40448793
PMCPMC12496335

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.