ArticleMethods in molecular biology (Clifton, N.J.)2025
Analysis of Epigenome-Wide Association Studies.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Epigenome-wide association studies (EWAS) investigate epigenetic modifications across the genome in relation to phenotypes of interest. The most commonly studied epigenetic modification in EWAS is DNA methylation, particularly at cytosine-phosphate-guanine (CpG) sites. Despite its potential, few EWAS have been conducted in bone diseases, and replication studies remain limited. Similar to genome-wide association studies, EWAS require rigorous steps for quality control of both samples and probes to ensure reliable results. Association analyses can focus on individual differentially methylated probes or adopt a regional approach to identify differentially methylated regions, providing insights into epigenetic contributions to disease.
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Registered trials
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