Evidence map›Paper›PMID 40448770›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Models of Rheumatoid Arthritis.

Bettina Grötsch, Aline Bozec, Georg Schett

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bettina GrötschUniversity of Erlangen-Nuremberg, Erlangen, Germany.
Aline BozecUniversity of Erlangen-Nuremberg, Erlangen, Germany. aline.bozec@uk-erlangen.de.
Georg SchettUniversity of Erlangen-Nuremberg, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mice models induced by immunization are used to study rheumatoid arthritis (RA) and its molecular mechanisms. In this article, we describe three models that mimic the clinical symptoms of human RA and can be applied to genetically modified mice. The collagen-induced arthritis (CIA), K/BxN serum-induced arthritis (SIA), and antigen-induced arthritis (AIA) models will be presented. To achieve this, we will describe their method of induction and how to analyze RA clinical scores and pathology characteristics. Finally, we will briefly discuss the main features and drawbacks of all three models.

Indexed as

Arthritis, ExperimentalArthritis, RheumatoidDisease Models, AnimalAnimalsHumansMiceAntigen-induced arthritisCollagen-induced arthritisK/BxN serum-induced arthritisRheumatoid arthritis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.