ArticleACS applied bio materials2025
Fast Lithium-Releasing Phosphate Glasses Promote the Resolution of Inflammation.
Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Mood stabilizers and systemic inflammatory burden in euthymic patients with bipolar disorder: a comparative study of lithium and valproate.Psychopharmacology · 2026Article
- Fabrication of Lithium/Strontium-Releasing Smart Bioactive Glasses with Anti-Inflammatory and Osteogenic Effects Tailored to Pathological Stages.Macromolecular bioscience · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delay in the resolution of inflammation has disastrous implications for tissue regeneration, but local anti-inflammatory signals could accelerate this process. To test this, phosphate-based bioactive glasses were fabricated to release lithium, an anti-inflammatory ion, at a range of ionic concentrations. Lithium release was contingent on the aluminum molar ratio within the glass formulation. Glasses that released lithium faster exerted greater anti-inflammatory effects on activated macrophages. These effects resulted from the inhibition of GSK3β activity and the promotion of CD206 expression. This study demonstrates the therapeutic potential of anti-inflammatory phosphate glasses in resolving inflammation in the regenerative environment.
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Registered trials
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