Evidence map›Paper›PMID 40448575›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2025

Use of Low-Value Cancer Treatments in Medicare Advantage Versus Traditional Medicare.

Jeah Jung, Caroline Carlin, Roger Feldman, Ge Song, Aaron Mitchell

Abstract readComparative Study
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeah JungDepartment of Health Administration and Policy, College of Public Health, George Mason University, Fairfax, VA.ORCID 0000-0001-7574-0677
Caroline CarlinDepartment of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN.ORCID 0000-0003-0813-3433
Roger FeldmanDivision of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, MN.
Ge SongDepartment of Health Administration and Policy, College of Public Health, George Mason University, Fairfax, VA.ORCID 0009-0000-4535-2112
Aaron MitchellDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0003-3639-3515

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Resource Use and Quality of Care in Medicare AdvantageR01AG069352 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI JUNG, JEAH · 2020 to 2023
$2.7M
NCI NIH HHS P30 CA008748NIA NIH HHS R01 AG069352
6 · The paper itself

Abstract

purposeMedicare Advantage (MA) provides beneficiaries an option to receive Medicare benefits from private plans. Although MA covers over half of the Medicare population, limited information exists about how utilization of cancer treatments in MA differs from traditional Medicare (TM). We compared use of low-value cancer treatments between MA and TM and analyzed variation in use of low-value cancer treatments across large MA insurers.

methodsUsing national Medicare data, we performed retrospective analyses of beneficiaries who had a new cancer diagnosis between 2016 and 2021 and who were at risk of receiving a low-value treatment: granulocyte-colony stimulating factors (GCSFs) for patients receiving low-risk chemotherapy, denosumab for castration-sensitive prostate cancer (CSPC), nab-paclitaxel instead of paclitaxel for breast or lung cancers, adding bevacizumab to carboplatin plus paclitaxel for ovarian cancer, and branded drugs or biologics for which generic or biosimilar versions existed.

resultsUse of any low-value cancer treatment was 1.7 percentage points lower in MA than in TM (34.2%

conclusionMA has lower use of low-value cancer treatments than TM, with varying degrees across large MA insurers. Efforts are needed to identify effective strategies to reduce use of low-value cancer treatments.

Indexed as

MedicareMedicare Part CNeoplasmsAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesUnited States

Identifiers

PMID40448575
PMCPMC12234249

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.