ArticleJournal of feline medicine and surgery2025
Evaluation of different constant rate infusions of dexmedetomidine in cats undergoing elective surgery.
Article in Journal of feline medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectivesThe objective of the study was to evaluate the effects of three constant rate infusions (CRIs) of dexmedetomidine (DEX; 1, 2 and 3 µg/kg/h) on cardiovascular, respiratory and analgesic outcomes in cats undergoing elective ovariectomy, aiming to identify an infusion rate that optimally balances analgesic benefits with minimal side effects.MethodsIn a randomised, controlled, blinded study, 73 healthy female cats were assigned to one of four groups: DEX1 (1 µg/kg/h), DEX2 (2 µg/kg/h), DEX3 (3 µg/kg/h) or a control group receiving saline solution (CTRL). Anaesthesia was maintained with isoflurane, and physiological variables, including heart rate (HR), blood pressure (BP), respiratory rate (RR) and end-tidal CO
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