Evidence map›Paper›PMID 40448304›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025

Conversion following minimally invasive attempt at simultaneous colorectal and liver resection does not affect 30-day postoperative overall morbidity.

Lawrence B Brown, Shannon N Radomski, Miloslawa Stem, Susan L Gearhart, Haniee Chung, Vincent J Obias, Alodia Gabre-Kidan

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In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lawrence B BrownColorectal Research Unit, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0001-6410-5774
Shannon N RadomskiColorectal Research Unit, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Miloslawa StemColorectal Research Unit, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Susan L GearhartColorectal Research Unit, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Haniee ChungColorectal Research Unit, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Vincent J ObiasColorectal Research Unit, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Alodia Gabre-KidanColorectal Research Unit, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Funding

The Effect Of Structural Racism On Racial And Geographic Disparities In Deceased Organ DonationF32DK132832 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BROWN, LAWRENCE · 2022 to 2024
$273k
Burroughs Wellcome FundMr. Edwin LewisNicholl Family FoundationNIDDK NIH HHS F32 DK132832NIH HHS
6 · The paper itself

Abstract

aimOver the past decade, minimally invasive surgery (MIS) approaches have been increasingly utilized for simultaneous colorectal cancer (CRC) and colorectal liver metastasis (CRLM). However, the impact of conversion to open surgery during MIS remains unclear. This study evaluates 30-day postoperative overall morbidity in patients undergoing simultaneous resection for CRC and CRLM tumours.

methodWe utilized the American College of Surgeons National Surgical Quality Improvement Program database from 2013 to 2022. Adults ≥18 years who underwent surgery for a simultaneous resection of CRC and CRLM were included. Propensity score matching was used to ascertain differences in surgical outcomes between those who underwent a planned open procedure and those who had an MIS that was converted to open.

resultsA total of 2306 patients were included in our study. Of these, the majority underwent a planned open procedure (n = 1831, 79.4%). Of the patients who underwent an MIS approach (n = 381, 20.6%), the majority had a laparoscopic procedure (n = 272, 71.4%) compared to a robotic approach (n = 109, 28.6%). There were significant differences between the three surgical groups by age group (P = 0.012), race (P < 0.001) and risk of procedure (P < 0.001). After propensity score matching, 94 patients remained in the planned open and MIS with conversion groups. There were no significant differences in 30-day postoperative outcomes between these two surgical groups.

conclusionPostoperative surgical outcomes between planned open and MIS converted to open procedures were similar. These findings imply that an MIS approach can be attempted for simultaneous resection of CRC and CRLM without adverse outcomes.

Indexed as

ColectomyColorectal NeoplasmsConversion to Open SurgeryHepatectomyLaparoscopyLiver NeoplasmsMinimally Invasive Surgical ProceduresPostoperative ComplicationsRobotic Surgical ProceduresAdultAgedDatabases, FactualFemaleHumansMaleMiddle Agedcolorectal cancercolorectal liver metastasesconversion to openlaparoscopic surgeryminimally invasive surgeryNational Surgical Quality Improvement Program (NSQIP)postoperative outcomespropensity score matchingrobotic surgerysimultaneous resection

Identifiers

PMID40448304
PMCPMC12143804

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.