Evidence map›Paper›PMID 40448279›Full record

ArticleJournal of burn care & research : official publication of the American Burn Association2025

Patient-Reported Pain and Itch Scores After a Course of Laser Therapy for the Treatment of Postburn Hypertrophic Scar Are Impacted by Mental Health Status.

Lia Mandavalli, Casey Meretta, Ishaan Nandwani, Taryn E Travis, Shawn Tejiram, Jeffrey W Shupp, Daniel M Schneider, Bonnie C Carney

Abstract read
In one paragraph

Article in Journal of burn care & research : official publication of the American Burn Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lia MandavalliFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States.
Casey MerettaFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States.ORCID 0009-0001-5328-2203
Ishaan NandwaniFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States.ORCID 0009-0001-9071-5944
Taryn E TravisFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States.ORCID 0000-0003-0519-4388
Shawn TejiramFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States.ORCID 0000-0002-5478-8935
Jeffrey W ShuppFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States.ORCID 0000-0002-4394-6416
Daniel M SchneiderDepartment of Surgery, Georgetown University School of Medicine, Washington, DC, United States.ORCID 0009-0006-7149-3051
Bonnie C CarneyFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States.ORCID 0000-0003-2292-4960

Funding

Institutional Career Development CoreKL2TR001432 · NCATS · GEORGETOWN UNIVERSITY · PI UMANS, JASON G · 2015 to 2024
$7.5M
NCATS NIH HHS KL2 TR001432
6 · The paper itself

Abstract

Burn injuries are often associated with physical scarring in addition to severe psychosocial consequences, including heightened pain and pruritus (itch). These symptoms can persist long after the injury and often become recalcitrant to standard treatments, such as gabapentin and antihistamines. Fractional ablative CO2 laser scar revision (FLSR) has gained popularity as an adjunctive therapy to address the limitations of existing treatments. However, despite this treatment, some patients continue to experience both symptoms, which negatively impacting their quality of life and daily functioning. A retrospective review of 110 patients receiving laser scar revision between 2018 and 2024 was conducted at a single institution, with patients divided into two cohorts: those with a diagnosed mental health condition and those without. Patients with a mental health diagnosis (MHD) reported a more significant reduction in pain and pruritus over the course of three laser sessions compared to those without an MHD. Despite these differences in perception, no variation was observed in the objective measures of scar healing between the cohorts. Gabapentin dosage was associated with reductions in pain perception, particularly in the MHD group. This finding suggests that mental health interventions may enhance the subjective experience of recovery, potentially through neuroplastic changes influenced by psychotherapy as compared to medications. This study underscores the need to integrate mental health care into the physical recovery of burn patients. Future research should investigate the long-term outcomes of combined mental health and scar therapy interventions to improve patient quality of life postinjury.

Indexed as

BurnsCicatrix, HypertrophicLasers, GasLaser TherapyMental HealthPruritusAdultFemaleGabapentinHumansMaleMiddle AgedPainPatient Reported Outcome MeasuresQuality of LifeRetrospective StudiesGabapentinhypertrophic scarpainpatient-reported outcome metricsprurituspsychosocial health

Identifiers

PMID40448279
PMCPMC12596634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.