Evidence map›Paper›PMID 40448226›Full record

ArticleCritical care (London, England)2025

Cardiovascular effects of hypertonic lactate solutions: acid-base or metabolic cause, or both?

Pedro J Freire Jorge, Rohan Boer, František Duška, Maarten M W Nijsten, Micah L A Heldeweg

Abstract readLetterComment
In one paragraph

Article in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Pedro J Freire JorgeDepartment of Critical Care, University Medical Center Groningen, Groningen, The Netherlands.
Rohan BoerDepartment of Anesthesiology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
František DuškaDepartment of Anesthesia and Intensive Care Medicine, The Third Faculty of Medicine, Charles University and FNKV University Hospital, Šrobárova 1150/50, 100 34, Prague, Czech Republic.
Maarten M W NijstenDepartment of Critical Care, University Medical Center Groningen, Groningen, The Netherlands.
Micah L A HeldewegDepartment of Anesthesiology, Amsterdam University Medical Centers, Amsterdam, The Netherlands. m.heldeweg@amsterdamumc.nl.

Funding

Supported by Czech Health Research Council (AZV ČR) NW26J-06-00090
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acid–baseBufferCarbon dioxideLactateMetabolicRespiratorySaline

Identifiers

PMID40448226
PMCPMC12123888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.