Evidence map›Paper›PMID 40448162›Full record

Observational studyHealth research policy and systems2025

Mind the (research) gap: a retrospective observational study on the utilization of new medical technologies and related research activities in German hospitals.

Tanja Rombey, Helene Eckhardt, Susanne Felgner, Marie Dreger, Alessandro Campione, Hanna Ermann, David Ehlig, Hendrikje Rödiger, Dimitra Panteli, Cornelia Henschke

Abstract readObservational Study
In one paragraph

Observational study in Health research policy and systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tanja RombeyDepartment of Health Care Management, Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-5777-9738
Helene EckhardtDepartment of Health Care Management, Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-3921-428X
Susanne FelgnerDepartment of Health Care Management and Berlin Centre for Health Economics Research (BerlinHECOR), Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-3140-0114
Marie DregerDepartment of Health Care Management and Berlin Centre for Health Economics Research (BerlinHECOR), Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-6879-604X
Alessandro CampioneDepartment of Health Care Management, Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-4959-8600
Hanna ErmannDepartment of Health Care Management, Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-6853-1375
David EhligChair of Health Economics, Policy and Management, School of Medicine (Med-HSG), Universität St. Gallen, St. Gallen, Switzerland.ORCID http://orcid.org/0000-0002-7092-7480
Hendrikje RödigerDepartment of Health Care Management, Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-0374-9837
Dimitra Panteli *Department of Health Care Management, Technische Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-2110-3335
Cornelia Henschke *Department of Health Care Management and Berlin Centre for Health Economics Research (BerlinHECOR), Technische Universität Berlin, Berlin, Germany. cornelia.henschke.1@tu-berlin.de.ORCID http://orcid.org/0000-0001-5261-2330

Funding

Bundesministerium für Bildung und Forschung 01EH1604A
6 · The paper itself

Abstract

objectivesHospitals play a major role in generating clinical evidence on new medical technologies. Thus far, the extent of German hospitals' contribution to the evidence base has not been sufficiently investigated. This study aims to: (1) examine the utilization of new medical technologies in German hospitals and its relationship to different hospital characteristics; (2) investigate the participation of German hospitals in research on these technologies and the association between hospital characteristics and research involvement; and (3) investigate the contribution of German hospitals to international research activities, including the levels of evidence of any studies conducted.

methodsUsing a systematically derived sample of 13 new medical technologies and various data sources, we retrospectively analyzed the utilization of and research activities by German hospitals between 2005 and 2017 and explored which hospital characteristics they were associated with. The data were analyzed descriptively and are expressed as bar plots, box plots, quartiles, and crude odds ratios (ORs).

resultsThe proportion of German hospitals using new technologies while also being involved in related clinical research was relatively low (ranging from 0.3% to 29.4%, except for transcatheter aortic valve implantation (TAVI), with 60.7%), particularly for prospective studies. Research involvement was positively associated with university hospital status, larger bed capacity, and public ownership. Overall, the research involving German hospitals predominantly consisted of single-arm studies and not randomized controlled trials (RCTs).

conclusionsOur study identified a gap between hospitals using new medical technologies and their involvement in evidence generation. This imbalance can contribute to uncertainty regarding the actual efficacy, effectiveness and safety of new medical technologies. To ensure evidence-based patient care, it is therefore essential to strengthen the link between research and practice, in both directions. A first step to achieve this could entail restricting the use of new medical technologies to specialized innovation centers (e.g., university hospitals, specialized hospitals) during the initial years of their utilization to ensure an adequate evidence base is generated before widespread implementation.

Indexed as

Biomedical ResearchBiomedical TechnologyHospitalsGermanyHospitals, UniversityHumansRetrospective Studies

Identifiers

PMID40448162
PMCPMC12124022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.