Evidence map›Paper›PMID 40448149›Full record

ArticleReproductive biology and endocrinology : RB&E2025

Egg donors' attitudes toward identifiability, offspring information, and genetic testing.

Emilie Lassen, Josephine G Lemmen, Guido Pennings, Anne-Bine Skytte

Abstract read
In one paragraph

Article in Reproductive biology and endocrinology : RB&E, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Letter to the editor.Journal of assisted reproduction and genetics · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emilie LassenCryos International Sperm & Egg Bank, Vesterbro Torv 3, Aarhus C, 8000, Denmark. eml@cryosinternational.com.
Josephine G LemmenCryos International Sperm & Egg Bank, Vesterbro Torv 3, Aarhus C, 8000, Denmark.
Guido PenningsDepartment of Philosophy and Moral Science, Bioethics Institute Ghent (BIG), Universiteit Gent, Blandijnberg 2, Ghent, B‑9000, Belgium.
Anne-Bine SkytteCryos International Sperm & Egg Bank, Vesterbro Torv 3, Aarhus C, 8000, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResearch on egg donors' perspectives regarding identifiability, donor-conceived offspring, and genetic testing remains limited, as most studies have focused on sperm donors. With the growing demand for donor eggs, understanding egg donors' attitudes is essential for ensuring ethical and effective donor programs. This study aims to address this gap by examining egg donors' views on identity-release and non-identity-release donation, the level of information they wish to receive about donor-conceived offspring, and their perspectives on genetic testing and expanded carrier screening.

methodsAn online questionnaire was sent to current and past oocyte donors at Cryos International in the United State between July 14th and September 1st, 2023. A total of 39 donors completed the questionnaire (27 ID-release donors and 12 non-ID-release donors).

resultsThe most frequent motivation for most egg donors was a desire to help childless couples, often in combination with financial compensation. There was no significant difference between non-ID release donors and ID-release donors in their motivation to help childless people (91.7% versus 85.2%). ID-release donors represented 69.2% of the participants. There were no significant differences between ID-release and non-ID-release donors regarding their attitudes toward receiving information about their donor-conceived offspring or openness about their donor status to others. Both donor groups expressed strong support for genetic testing and extended carrier screening. There was a significant difference regarding contact with donor-conceived children in line with their choice of anonymity type. Non-ID release donors would not enjoy contact with their donor offspring if they were traced and they hoped they would not be traced.

conclusionsOffering donors the choice between ID-release and non-ID-release donation facilitates broader donor recruitment. The demographic and motivational characteristics of the donors were similar, and both groups demonstrated positive attitudes toward genetic testing and extended carrier screening. Further research is needed to explore the long-term attitudes and experiences of egg donors regarding donation outcomes.

Indexed as

AttitudeGenetic TestingOocyte DonationTissue DonorsAdultFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAttitudesEgg donorsGenetic testingIdentifiabilityOffspringOocyte donation

Identifiers

PMID40448149
PMCPMC12123844

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.