Evidence map›Paper›PMID 40448076›Full record

ArticleJournal of orthopaedic surgery and research2025

Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures.

Chengming Li, Hangyu Ji, Daping Cui, Suyang Zhuang, Cong Zhang

Abstract read
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In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Serum parathyroid hormone and risk of sarcopenia: a meta-analysis.Journal of orthopaedic surgery and research · 2025
    Pooled it
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Crosstalk between osteoporosis and fat-infiltrated psoas at the upper lumbar levels.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chengming LiDepartment of Spinal Surgery Center, Zhongda Hospital Southeast University, Nanjing, 210009, People's Republic of China.ORCID http://orcid.org/0000-0003-0755-1780
Hangyu JiDepartment of Spinal Surgery Center, Zhongda Hospital Southeast University, Nanjing, 210009, People's Republic of China.
Daping CuiDepartment of Orthopedics, Shenzhen Bao'an District Central Hospital, Shenzhen, 518100, People's Republic of China.
Suyang ZhuangDepartment of Spinal Surgery Center, Zhongda Hospital Southeast University, Nanjing, 210009, People's Republic of China.
Cong ZhangDepartment of Spinal Surgery Center, Zhongda Hospital Southeast University, Nanjing, 210009, People's Republic of China. zhangcong19@hotmail.com.ORCID http://orcid.org/0009-0007-4530-2052

Funding

Fundamental Research Funds for the Central Universities 2242020K40156Jiangsu Entrepreneurship and Innovation Doctors 202030338National Natural Science Foundation of China 82202768Open Project Programme of the Key Base for Standardized Training for General Physicans, Zhongda Hospital, Southeast University ZDZYJD-QK-2022-16Zhongda Hospital Affiliated to Southeast University, Jiangsu Province High-Level Hospital Construction Funds GSP-LCYJFH20
6 · The paper itself

Abstract

objectiveThis study aimed to investigate whether sarcopenia affects residual back pain (RBP) after percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCF).

methodsWe retrospectively analyzed the clinical data of 231 patients with single-segment OVCF treated with PKP between January 2023 and December 2023. Postoperative RBP was assessed at 1 month using the visual analogue scale (VAS). Patients with a VAS score ≥ 4 were classified as the RBP group, while those with a score < 4 served as controls. Sarcopenia was diagnosed using the skeletal muscle mass index (SMI), calculated by dividing the cross-sectional muscle area at the T12 vertebral level (measured via chest CT) by height squared. Univariate analysis compared clinical and imaging data between groups, and binary logistic regression identified risk factors.

resultNo significant differences were observed between groups in gender, BMI, surgical segment, hypertension, diabetes, or coronary heart disease (P > 0.05). However, age, BMD, SMI, bone cement usage, and sarcopenia prevalence differed significantly (P < 0.05). Binary logistic regression identified BMD and sarcopenia as independent risk factors for RBP after PKP.

conclusionOVCF patients with sarcopenia have a higher likelihood of postoperative RBP, with an incidence approximately twice that of non-sarcopenic patients. Preoperative sarcopenia screening should be prioritized, and postoperative anti-muscular atrophy therapy actively implemented.

Indexed as

Back PainFractures, CompressionKyphoplastyOsteoporotic FracturesPostoperative ComplicationsSarcopeniaSpinal FracturesAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsOsteoporotic vertebral compression fracturePercutaneous kyphoplastyResidual back painSarcopenia

Identifiers

PMID40448076
PMCPMC12124072

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.