Evidence map›Paper›PMID 40448049›Full record

ArticleBMC ophthalmology2025

Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations.

Yixiao Li, Liang Wang, Dan Song, Bingxuan Jiao, Jing Li, Jie Zhou, Lei Guo

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yixiao LiDepartment of Cheeloo College of Medicine, Shandong University, Jinan, 250001, China.
Liang WangDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, China.
Dan SongDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, China.
Bingxuan JiaoDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, China.
Jing LiDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, China.
Jie ZhouDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, China.
Lei GuoDepartment of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, China. etjrxgl@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigated the treatment outcomes of ultrasound-guided sclerotherapy with pingyangmycin for periorbital lymphatic malformations (LMs).

methodA retrospective study of patients with periorbital LMs who underwent ultrasound-guided sclerotherapy in our department between 2017 and 2024 was conducted.

resultsOne boy and seven girls with periorbital LMs were analyzed. Four cases had intraorbital lesions, two cases had lesions of the eyelids, and two cases had mixed lesions. Eight children underwent 13 sclerotherapy sessions, fluid was able to be withdrawn with a median amount of aspirate of 2 ml. After treatment, one of the eight children was lesion not seen on imaging, six showed strong improvement, and one showed weak improvement. None of the children experienced procedure-related adverse reactions.

conclusionsUltrasound-guided sclerotherapy is a treatment modality for periorbital LMs with good efficacy and few potential risks.

Indexed as

Antibiotics, AntineoplasticBleomycinLymphatic AbnormalitiesSclerotherapyUltrasonography, InterventionalChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesSclerosing SolutionsTreatment OutcomeAntibiotics, AntineoplasticbleomycetinBleomycinSclerosing SolutionsLymphatic malformationsPeriorbitalPingyangmycinSclerotherapyUltrasound-guided

Identifiers

PMID40448049
PMCPMC12123770

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.