Evidence map›Paper›PMID 40448038›Full record

ArticleBMC ophthalmology2025

Incidence and risk factors of retinopathy of prematurity in Palestine: a retrospective cohort study, 2024.

Waseem Shehadeh, Fathi Milhem, Orabi Hajjeh, Mohammad AbuZahra, Anas Abu Zahra, Zeineddin Etkaidek, Amir Atawna, Jawad Hassoun, Sameeha Shweiki, Zaher Nazzal

Abstract readMulticenter Study
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Waseem ShehadehDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Fathi MilhemDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Orabi HajjehDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Mohammad AbuZahraDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Anas Abu ZahraDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Zeineddin EtkaidekDepartment of Pediatrics, Makassed Hospital, East Jerusalem, Palestine.
Amir AtawnaDepartment of Neonatology, Makassed Hospital, Al-Quds University, East Jerusalem, Palestine.
Jawad HassounDepartment of Pediatrics, Rafidia Hospital- Palestinian Ministry of Health, Nablus, Palestine.
Sameeha ShweikiRetina Department, Hugo Chavez Hospital- Palestinian Ministry of Health, Turmus Ayya,, Palestine. drs.shweiki@gmail.com.
Zaher NazzalDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine. znazzal@najah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetinopathy of prematurity (ROP) is a major, yet preventable, cause of childhood blindness. This study aimed to determine the incidence in Palestine and the risk factors for ROP development.

methodsWe conducted a retrospective cohort study involving 520 preterm infants born between January 2020 and December 2023 in 7 major Palestinian Neonatal Intensive Care Units (NICUs) who were screened for ROP. We examined a range of clinical variables from medical records to explore their relationship with the development of the disease.

resultsThe incidence of ROP and severe type 1 ROP was 42.9% and 8.8%, respectively. Many risk factors were significant in univariate analysis, such as respiratory distress syndrome (RDS), the duration of mechanical ventilation, the number of blood transfusions needed, and the need for supplemental oxygen at 28 days. However, only lower gestational age (OR, 10.4; 95% CI, 3.66-29.9; p < 0.001), lower birth weight (OR, 2.5; 95% CI, 1.3-4.7; p = 0.006), lower postmenstrual age at the time of diagnosis, and multiple gestations were significant in multivariate analysis.

conclusionROP is a significant problem in Palestine, with a relatively higher incidence than in neighboring countries. Considering the statistically significant variables in the clinical practice will prevent missing severe cases that may progress to blindness.

Indexed as

Retinopathy of PrematurityBirth WeightFemaleGestational AgeHumansIncidenceInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleMiddle EastRetrospective StudiesRisk FactorsIncidencePalestineRetinopathy of prematurityRisk factors

Identifiers

PMID40448038
PMCPMC12123855

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.