Observational studyEuropean journal of pediatrics2025
Impact of complex chronic diseases and life-limiting condition status on paediatric hospitalization: observational study.
Observational study in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Pediatric palliative care in practice: real-world service utilization and care pathways in a regional Italian health system.European journal of pediatrics · 2026Observational
- Did government subsidy program improve quality of care for children with complex chronic conditions in children's hospitals? A quasi-experimental study in South Korea.Clinical and experimental pediatrics · 2026Article
- Identification and characteristics of children with complex chronic diseases in the paediatric ward of a tertiary hospital: a prospective study.European journal of pediatrics · 2026Article
- The assessment of continuity of care and care coordination for Children and Youth with Special Health Care Needs (CYSHCN): a cross-sectional descriptive study in Northeastern Italy.Italian journal of pediatrics · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Children with medical complexity (CMC) and life-limiting conditions (LLCs) have a high utilization of healthcare resources. This study aims to assess the impact of CMC and LLC on hospitalization in the Basque Public Health System (BPHS) and to compare CMC to LLC to characterize inpatient health utilization. This is a retrospective observational study including all admissions of paediatric patients (< 19 years) to the BPHS during the period 2018-2020. The Pediatric Medical Complexity Algorithm and the Hain Directory of Life-Limiting Conditions were used to identify children with complex chronic diseases (C-CDs) and LLCs, respectively. Inpatient health utilization and in-hospital mortality of patients with C-CD and LLC were compared to those without these conditions. A total of 34,555 admissions were recorded for 26,196 patients during the study period. Patients with C-CD and LLC accounted for 15.4% and 14.4% of these admissions, respectively. Patients with LLC were more likely to require respiratory or hemodynamic support and device placement than patients with C-CD. Children with LLC and C-CD exhibited a higher frequency and length of stay of both general and ICU admissions than those without these conditions. Eight out of ten patients who died during admission had C-CD and/or LLC, with a higher probability of in-hospital death among patients with LLC.
conclusionA considerable proportion of admissions among children was attributed to patients with C-CD and LLC. Both exhibited substantial utilization of hospital resources and high in-hospital mortality, being more pronounced among patients with LLC. Further studies focused on cost/expenditures are needed within a publicly insured health system. WHAT IS KNOWN: • Children with medical complexity (CMC) consume a lot of healthcare resources, and their in-hospital mortality is high. There are several ways to identify CMC in health datasets. Both children with chronic complex disease (C-CD) and life-limiting conditions (LLC) are CMC. WHAT IS NEW: • There is an important overlap between children classified as having C-CD and those with LLC. Both groups exhibited substantial utilization of hospital resources and high in-hospital mortality, being more pronounced among patients with LLC.
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