ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025
Case series of functional non epileptic seizures (PNES) in patients with brain tumors.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Consequences of Acute Presentations of Functional Neurological Disorders in Neuro-Oncology Patients: Case Series and Systematic Review.Brain and behavior · 2025Pooled it
- Nanomaterial-enhanced biosensors for traumatic brain injury biomarker detection: a review of analytical performance, machine learning integration, clinical validation, and point-of-care translation.Frontiers in neurology · 2026Review
- Clinical insights on "Case series of functional non epileptic seizures (PNES) in patients with brain tumors".Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
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13 authors.
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Abstract
purposeFunctional (Psychogenic) non epileptic seizures (PNES) are events which mimic epileptic seizures without ictal electrical findings on the EEG recording during the events. Diagnosis of PNES is made by correlating the clinical presentation with the lack of ictal activity as diagnosed by video EEG (VEEG) and is crucial for proper decision-making regarding management. Patients with brain tumors have a high prevalence of epileptic seizures. However, clinician's awareness of PNES in those patients is often insufficient. PATIENTS AND
methodsWe collected data regarding 6 patients with brain tumors which were followed-up in the neuro-oncology unit in Sheba medical center and were diagnosed with epilepsy, along with PNES according to VEEG.
resultsWe describe data regarding 6 patients aged 20-68, four of them females, with different brain tumors and in various stages of the disease. PNES were mostly focal, and a clear trigger was identified in four patients. Improvement in PNES frequency alongside a reduction in anti-seizure medicaions followed diagnosis of PNES in 5 out of the 6 patients.
conclusionsIn our case series, PNES were usually focal, and patients did not have all the risk factors associated with PNES in the general population. PNES frequency was unrelated to oncological status. Diagnosis of PNES with open discussion reduced PNES frequency and dosages of anti-seizure medications in our patients.
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