ArticlePediatric research2026
Cognitive development at late infancy and school age in children cooled for neonatal encephalopathy.
Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Brain imaging as a predictor of neurodevelopmental outcomes in neonatal encephalopathy.Pediatric research · 2026Article
- From differential to definitive: diagnosing and treatment of neonatal encephalopathy.Pediatric research · 2025Article
- The future of neurodevelopmental disabilities.Pediatric research · 2025Article
- Antibiotic use in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia: time to rethink universal empirical treatment.European journal of pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated the association and individual changes in cognitive scores between late infancy and early school age in children cooled for neonatal encephalopathy secondary to perinatal asphyxia (NE) who did not develop cerebral palsy.
methodsWe included 50 children born ≥35 weeks gestation cooled for NE who did not develop cerebral palsy. We assessed cognition using an average of cognitive and language composite scores (CLC) from Bayley Scales of Infant and Toddler Development (Bayley-III) at 18-21 months and full-scale IQ (FSIQ) on Wechsler Intelligence Scale for Children (WISC-IV) at 6-8 years. Linear regression was used to assess the association between CLC and FSIQ.
resultsOur cohort's mean gestation was 39.8 (SD 1.6) weeks; 59% male. 80% had moderate NE. CLC scores were significantly associated with FSIQ (Coef 0.45 (95% CI: 0.17, 0.72), R
conclusionBayley-III underestimates the delay at school age in children cooled for NE. Childhood IQ after NE appeared to be patterned by local deprivation. IMPACT: Bayley-III underestimates school-age delays in children cooled for neonatal encephalopathy secondary to perinatal asphyxia (NE). Around 45% of children's cognitive scores moved to a lower developmental range at school age. Increasing the Bayley-III threshold to 95 failed to identify nearly two-thirds of children with IQ < 85. Childhood IQ after NE appeared to be patterned by local deprivation. Longitudinal monitoring of children cooled for neonatal encephalopathy secondary to perinatal asphyxia is needed to support their cognitive development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.