Evidence map›Paper›PMID 40447792›Full record

ArticleScientific reports2025

Impact of antibacterial therapeutic agents on biofilm-tissue interactions in a 3D implant-tissue-oral-bacterial-biofilm model.

Carina Mikolai, Kathrin Wöll, Muhammad Imran Rahim, Andreas Winkel, Christine S Falk, Meike Stiesch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carina Mikolai *Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Mikolai.Carina@mh-hannover.de.ORCID http://orcid.org/0000-0002-8816-7766
Kathrin Wöll *Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Muhammad Imran Rahim *Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Andreas WinkelDepartment of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Christine S FalkInstitute of Transplant Immunology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Meike StieschDepartment of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Stiesch.Meike@mh-hannover.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial biofilms on dental implants can lead to peri-implant infections and demonstrate a remarkable ability to evade host immunity and resist antibiotics. Advanced in vitro models, such as the three-dimensional implant-tissue-oral-bacterial-biofilm model (INTER

Indexed as

Anti-Bacterial AgentsBacteriaBiofilmsDental ImplantsMouth MucosaAmoxicillinChlorhexidineCiprofloxacinDoxycyclineHumansModels, BiologicalTissue Inhibitor of Metalloproteinase-1AmoxicillinAnti-Bacterial AgentsChlorhexidineCiprofloxacinDental ImplantsDoxycyclineTissue Inhibitor of Metalloproteinase-13D cell culture modelAntibioticsCytokinesHistologyMultispecies biofilmsPeri-implantitis

Identifiers

PMID40447792
PMCPMC12125177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.