Evidence map›Paper›PMID 40447726›Full record

ArticleScientific reports2025

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization.

Venkata Nagaraju Thatha, M Ganesh Karthik, Venu Gopal Gaddam, D Pramodh Krishna, S Venkataramana, Kranthi Kumar Lella, Udayaraju Pamula

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Venkata Nagaraju ThathaDepartment of Information Technology, MLR Institute of Technology, Hyderabad, India.
M Ganesh KarthikDepartment of Computer Science and Engineering, GITAM School of Technology, GITAM University-Bengaluru Campus, Bengaluru, India.
Venu Gopal GaddamDepartment of CSE (AIML), B V Raju Institute of Technology, Narsapur, India.
D Pramodh KrishnaDepartment of Computer Science and Engineering, Koneru Lakshmaiah Education Foundation, Vijayawada, India.
S VenkataramanaDepartment of Information Technology, SRKR Engineering College, Bhimavaram, 534204, India.
Kranthi Kumar LellaSchool of Computer Science and Engineering, VIT-AP University, Vijayawada, India. kranthi1231@gmail.com.
Udayaraju PamulaDepartment of CSE, School of Engineering and Sciences, SRM University-AP, Amaravati, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer diagnosis remains a crucial challenge in medical research, necessitating accurate and automated detection methods. This study introduces an advanced deep learning framework for histopathological image classification, integrating AlexNet and Gated Recurrent Unit (GRU) networks, optimized using the Hippopotamus Optimization Algorithm (HOA). Initially, DenseNet-41 extracts intricate spatial features from histopathological images. These features are then processed by the hybrid AlexNet-GRU model, leveraging AlexNet's robust feature extraction and GRU's sequential learning capabilities. HOA is employed to fine-tune hyperparameters, ensuring optimal model performance. The proposed approach is evaluated on benchmark datasets (BreakHis and BACH), achieving a classification accuracy of 99.60%, surpassing existing state-of-the-art models. The results demonstrate the efficacy of integrating deep learning with bio-inspired optimization techniques in breast cancer detection. This research offers a robust and computationally efficient framework for improving early diagnosis and clinical decision-making, potentially enhancing patient outcomes.

Indexed as

Breast NeoplasmsDeep LearningImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedAlgorithmsFemaleHumansNeural Networks, ComputerAlexNetBreast CancerDeep learningDenseNet-41Gated recurrent unit (GRU)Hippopotamus optimization algorithm (HOA)Histopathological image classification

Identifiers

PMID40447726
PMCPMC12125401

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.