Evidence map›Paper›PMID 40447652›Full record

ArticleScientific data2025

MCOA: A Comprehensive Multimodal Dataset for Advancing Deep Learning in Corneal Opacity Assessment.

Xinyu Ma, Jianxia Fang, Yaqi Wang, Zhichao Hu, Zhe Xu, Sha Zhu, Weijia Yan, Mengqi Chu, Jingwei Xu, Siting Sheng and 5 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xinyu Ma *Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Jianxia Fang *Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Yaqi WangInnovation Center for Electronic Design Automation Technology, Hangzhou Dianzi University, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0002-4627-3392
Zhichao HuInnovation Center for Electronic Design Automation Technology, Hangzhou Dianzi University, Hangzhou, Zhejiang, China.
Zhe XuEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Sha ZhuEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Weijia YanEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Mengqi ChuEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Jingwei XuEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Siting ShengEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Chujun LiuEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Mingxuan ZhangEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Ce ShiEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China. ceshi0203@zju.edu.cn.
Gangyong JiaInnovation Center for Electronic Design Automation Technology, Hangzhou Dianzi University, Hangzhou, Zhejiang, China. gangyong@hdu.edu.cn.
Wen XuEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China. xuwen2003@zju.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 52203191National Natural Science Foundation of China (National Science Foundation of China) 82271042National Natural Science Foundation of China (National Science Foundation of China) 82301187
6 · The paper itself

Abstract

Corneal opacity remains a major global cause of vision impairment. Its severity is typically assessed subjectively by clinicians using slit lamp examinations of the anterior segment. While anterior segment optical coherence tomography (AS-OCT) provides high-resolution cross-sectional images of the cornea, capturing subtle structural changes, the combination of AS-OCT images with anterior segment photographs delivers a more comprehensive view of the cornea. However, the absence of large-scale, high-quality datasets hinders the development of deep learning algorithms for this purpose. To bridge this gap, we established the most extensive corneal opacity dataset available. The dataset included a total of 6,272 AS-OCT images and 392 corresponding anterior segment photographs. Each image of patients with corneal opacity was carefully annotated to include detailed cornea and corneal opacity information. This robust dataset represented a significant step forward in leveraging deep learning for corneal opacity recognition, empowering AI-driven clinical decision-making and facilitating the creation of personalized treatment plans for affected patients.

Indexed as

Corneal OpacityDeep LearningCorneaHumansTomography, Optical Coherence

Identifiers

PMID40447652
PMCPMC12125280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.