Evidence map›Paper›PMID 40447369›Full record

ArticleJACC. Case reports2025

Percutaneous Mechanical Aspiration of an Aortic Root Thrombus Causing a Myocardial Infarction.

Goyal Umadat, Nahyr Lugo-Fagundo, Carolyn Landolfo, Peter Pollak, Abdallah El Sabbagh

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Goyal UmadatDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Nahyr Lugo-FagundoDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Carolyn LandolfoDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Peter PollakDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Abdallah El SabbaghDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA. Electronic address: elsabbagh.abdallah@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular assist devices (LVADs) are critical for patients with end-stage cardiomyopathy but complications, such as aortic root thrombus (ART), are present in up to 10% of cases. ART management is challenging, with limited therapeutic options. CASE SUMMARY: A 54-year-old female with an LVAD presented with acute chest pain and a thrombus in the left coronary cusp. She was treated with successful percutaneous mechanical aspiration (PMA) of the aortic root and coronary arteries. Her international normalized ratio target was increased, and she has not had a recurrence of her ART. DISCUSSION: ART in LVAD patients often arises from impaired aortic valve opening, promoting thrombus formation. This case demonstrates the utility of PMA as a safe and effective alternative to surgical removal. TAKE-HOME MESSAGES: ART is a critical complication of LVADs, requiring prompt diagnosis and treatment. PMA can offer a definitive and safe treatment option for ART in select patients.

Indexed as

aortachronic heart failurethrombus

Identifiers

PMID40447369
PMCPMC12235480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.