Evidence map›Paper›PMID 40447021›Full record

ArticleEnvironmental research2025

Ambient air pollution in critical windows of exposure and spontaneous miscarriage in a preconception cohort.

Anne Marie Z Jukic, Kathryn S Konrad, Ian D Buller, Johanna R Jahnke, Ana Rosen Vollmar, D Robert McConnaughey, Alexander P Keil, Anne Z Steiner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne Marie Z JukicEpidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC, 27709, USA. Electronic address: jukica@niehs.nih.gov.
Kathryn S KonradDLH, LLC, Bethesda, MD, 20817, USA.
Ian D BullerDLH, LLC, Bethesda, MD, 20817, USA.
Johanna R JahnkeEpidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC, 27709, USA.
Ana Rosen VollmarEpidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC, 27709, USA.
D Robert McConnaugheyWestat, USA.
Alexander P KeilOccupational and Environmental Epidemiology Branch, National Cancer Institute, NIH, DHHS, Rockville, MD, 20850, USA.
Anne Z SteinerDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Environmental influences on fertility and reproductive healthZIAES103333 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JUKIC, ANNE MARIE · 2019 to 2025
$7.3M
STUDIES OF OCCUPATIONAL CANCER--PESTICIDESZ01CP010119 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ALAVANJA, MICHAEL · 1996 to 2008
$5.0M
Biomarkers of InfertilityR01HD067683 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STEINER, ANNE ZWEIFEL · 2011 to 2015
$2.7M
An investigation of vitamin D in human fertility and early pregnancyR00HD079659 · NICHD · YALE UNIVERSITY · PI JUKIC, ANNE MARIE ZAURA · 2015 to 2017
$725k
Time to ConceiveR21HD060229 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STEINER, ANNE ZWEIFEL · 2009 to 2010
$407k
Intramural NIH HHS Z01 CP010119Intramural NIH HHS ZIA ES103333NICHD NIH HHS R00 HD079659NICHD NIH HHS R01 HD067683NICHD NIH HHS R21 HD060229
6 · The paper itself

Abstract

Air pollution may increase spontaneous miscarriage risk, potentially through inflammation. Prior studies are heterogeneous, and none have used a mixtures approach. We used data from participants who conceived in a prospective time-to-pregnancy study (N = 446) in North Carolina to examine spontaneous miscarriage, defined as a positive home pregnancy test and a self-reported pregnancy loss before gestational week 20 (N = 101). We characterized average and peak exposure to PM

Indexed as

Abortion, SpontaneousAir PollutantsAir PollutionEnvironmental ExposureAdultCohort StudiesFemaleHumansMaleNorth CarolinaParticulate MatterPregnancyProportional Hazards ModelsProspective StudiesYoung AdultAir PollutantsParticulate MatterAmbient air pollutionMiscarriageOzonePregnancy lossVitamin D

Identifiers

PMID40447021
PMCPMC12285901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.