Evidence map›Paper›PMID 40446833›Full record

ArticlePhysics in medicine and biology2025

Modeling prompt gamma (PG) emission, detection and imaging in real patient anatomy using a novel Compton camera for dose verification in proton therapy.

V R Sharma, Z Jiang, S Mossahebi, E Shakeri, A Chalise, M K Gobbert, S W Peterson, J C Polf, L Ren

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

V R SharmaDepartment of Radiation Oncology, School of Medicine, University of Maryland, Baltimore, MD 21201, United States of America.ORCID 0000-0002-4254-5653
Z JiangDepartment of Radiation Oncology, Stanford University, Stanford, CA 94304, United States of America.
S MossahebiMaryland Proton Treatment Center, Baltimore, MD, United States of America.
E ShakeriDepartment of Mathematics and Statistics, University of Maryland Baltimore County, Baltimore, MD, United States of America.
A ChaliseDepartment of Radiation Oncology, School of Medicine, University of Maryland, Baltimore, MD 21201, United States of America.
M K GobbertDepartment of Mathematics and Statistics, University of Maryland Baltimore County, Baltimore, MD, United States of America.ORCID 0000-0003-1745-2292
S W PetersonDepartment of Physics, University of Cape Town, Rondebosch 7700, South Africa.
J C PolfM3D, Ann Arbor, MI 48108, United States of America.
L RenDepartment of Radiation Oncology, School of Medicine, University of Maryland, Baltimore, MD 21201, United States of America.ORCID 0009-0005-2384-5676

Funding

eXtended Modular ANthropomorphic (XMAN) phantom for Imaging and Treatment Optimization in Radiotherapy.R01EB032680 · NIBIB · UNIVERSITY OF MARYLAND BALTIMORE · PI REN, LEI, YANG, XIAOFENG · 2022 to 2025
$2.4M
3-dimensional prompt gamma imaging for online proton beam dose verificationR01CA279013 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Jerimy C. Polf, Lei Ren · 2023 to 2026
$1.9M
3D In vivo dosimetry for FLASH proton therapyU01CA288351 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Yong Chen, Lei Ren · 2024 to 2026
$1.8M
NCI NIH HHS R01 CA279013NCI NIH HHS U01 CA288351NIBIB NIH HHS R01 EB032680
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gamma CamerasGamma RaysProton TherapyRadiation DosageHumansImage Processing, Computer-AssistedMonte Carlo MethodRadiotherapy DosageRadiotherapy Planning, Computer-AssistedCompton cameraskernel weighted back projectionMonte Carlo simulationsprompt gamma imagingproton therapy

Identifiers

PMID40446833
PMCPMC13022849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.