Evidence map›Paper›PMID 40446017›Full record

ArticleScience immunology2025

Human LY9 governs CD4

Masato Ogishi, Julia Puchan, Rui Yang, Andrés Augusto Arias, Ji Eun Han, Tina Nguyen, Rebeca Gutiérrez-Cózar, Clément Conil, Yoann Seeleuthner, Darawan Rinchai and 43 more

Abstract read
In one paragraph

Article in Science immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

53 authors.

Masato OgishiSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0003-2421-7389
Julia PuchanInstitute of Microbiology, ETH Zürich, Zürich, Switzerland.ORCID 0000-0003-0284-3629
Rui YangSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0003-4427-2158
Andrés Augusto AriasSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Ji Eun HanSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0003-1112-9320
Tina NguyenGarvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.ORCID 0000-0003-0709-3636
Rebeca Gutiérrez-CózarImmunology Unit, Department of Biomedical Sciences, Faculty of Medicine and Medical Sciences, University of Barcelona, Barcelona, Spain.ORCID 0000-0003-0348-3223
Clément ConilLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Yoann SeeleuthnerLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Darawan RinchaiSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0001-8851-7730
Peng ZhangSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0002-6129-567X
Khoren PonsinSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Matthieu ChaldebasSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0002-4920-3947
Yi FengSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0002-2393-1700
Anna-Lena NeehusLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.ORCID 0000-0002-8573-6820
Ottavia M DelmonteImmune Deficiency Genetics Section, Laboratory of Host Defenses, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-4772-0799
Taushif KhanDepartment of Human Immunology, Research Branch, Sidra Medicine, Doha, Qatar.ORCID 0000-0002-7917-8965
Nils LandegrenCenter for Molecular Medicine, Department of Medicine (Solna), Karolinska Institute, Stockholm, Sweden.
Daniel ErikssonCenter for Molecular Medicine, Department of Medicine (Solna), Karolinska Institute, Stockholm, Sweden.ORCID 0000-0001-5473-3312
Jonathan BohlenLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.ORCID 0000-0003-0458-9484
Jessica N PeelSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Iris FagniezSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0009-0009-9900-3001
Simon J PelhamSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0002-3119-662X
Wei-Te LeiSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0003-1677-8901
Maya ChrabiehLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Candice LaineLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.ORCID 0000-0003-3258-6969
Hind OuairClinical Immunology, Infection, and Auto-Immunity Laboratory (LICIA), Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.
Ibtihal BenhsaienDepartment of Pediatric Infectious and Immunological Diseases, Children's Hospital, Averroes University Hospital, Casablanca, Morocco.ORCID 0000-0001-5727-9629
Ahmed AbidDepartment of Pulmonology, Mohammed V Military Hospital, Rabat, Morocco.ORCID 0000-0003-4885-6572
Ismail Abderrhamani GhorfiDepartment of Pulmonology, Mohammed V Military Hospital, Rabat, Morocco.ORCID 0000-0001-6403-0098
Hicham SouhiDepartment of Pulmonology, Mohammed V Military Hospital, Rabat, Morocco.ORCID 0000-0003-3183-1627
Hanane OuazzaniDepartment of Pulmonology, Mohammed V Military Hospital, Rabat, Morocco.
Rafik AnissDepartment of Pulmonology, Mohammed V Military Hospital, Rabat, Morocco.
D Sean RimintonImmunology Department, Concord Repatriation General Hospital, Hospital Road, Concord, New South Wales, Australia.ORCID 0000-0002-9953-9959
Olle KämpeCenter for Molecular Medicine, Department of Medicine (Solna), Karolinska Institute, Stockholm, Sweden.ORCID 0000-0001-6091-9914
Stuart E TurveyDepartment of Pediatrics, British Columbia Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-1599-1065
Nico MarrDepartment of Human Immunology, Research Branch, Sidra Medicine, Doha, Qatar.ORCID 0000-0002-1927-7072
Luigi D NotarangeloImmune Deficiency Genetics Section, Laboratory of Host Defenses, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-8335-0262
Nevin HatipogluPediatric Infectious Diseases Unit, Bakirkoy Dr Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.ORCID 0000-0003-2858-0150
Aziz BousfihaDepartment of Pediatric Infectious and Immunological Diseases, Children's Hospital, Averroes University Hospital, Casablanca, Morocco.ORCID 0000-0002-5011-9873
Tayfun OzcelikDepartment of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.ORCID 0000-0001-5937-1082
Jamila El BaghdadiGenetics Unit, Mohamed V Military Hospital, Hay Riad, Rabat, Morocco.ORCID 0000-0002-1920-2310
Aurelie CobatLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.ORCID 0000-0001-7209-6257
Cindy S MaGarvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.ORCID 0000-0001-5387-8413
Laurent AbelSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0001-7016-6493
Anne PuelSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0003-2603-0323
Jacinta BustamanteSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0002-3439-2482
Pablo EngelImmunology Unit, Department of Biomedical Sciences, Faculty of Medicine and Medical Sciences, University of Barcelona, Barcelona, Spain.ORCID 0000-0001-8410-252X
Philippe GrosMcGill Research Center on Complex Traits, Montreal, Quebec, Canada.ORCID 0000-0002-0114-1978
Stuart G TangyeGarvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.ORCID 0000-0002-5360-5180
Federica SallustoInstitute of Microbiology, ETH Zürich, Zürich, Switzerland.ORCID 0000-0003-3750-2752
Stéphanie Boisson-DupuisSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0002-7115-116X
Jean-Laurent CasanovaSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.ORCID 0000-0002-7782-4169

Funding

Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
Tissue and organ specific human B cell immunity: Supplement - Metabolic Risk Factors and Inflammation in PASC DevelopmentU19AI142737 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TECTOR, A JOSEPH · 2019 to 2023
$19.7M
Pharmacology & ImmunoPathology (PIP) CoreU19AI162568 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI EHRT, SABINE, GLICKMAN, MICHAEL S · 2021 to 2025
$13.0M
Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasisR01AI127564 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Jean-Laurent Casanova · 2017 to 2026
$4.8M
Genome-Wide Dissection of Mendelian Susceptibility to Mycobacterial DiseaseR01AI095983 · NIAID · ROCKEFELLER UNIVERSITY · PI BUSTAMANTE, JACINTA, CASANOVA, JEAN-LAURENT · 2021 to 2025
$2.5M
Howard Hughes Medical InstituteNCATS NIH HHS UL1 TR001866NIAID NIH HHS R01 AI095983NIAID NIH HHS R01 AI127564NIAID NIH HHS U19 AI142737NIAID NIH HHS U19 AI162568
6 · The paper itself

Abstract

CD4

Indexed as

CD4-Positive T-LymphocytesInterferon-gammaMycobacterium tuberculosisSignaling Lymphocytic Activation Molecule FamilyTh1 CellsTuberculosisFemaleHumansMaleInterferon-gammaSignaling Lymphocytic Activation Molecule Family

Identifiers

PMID40446017
PMCPMC12242830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.