ArticlePloS one2025
Schistosoma mansoni infection causes consistent changes to the fecal bacterial microbiota of mice across and within sites.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Eggs of Schistosoma mansoni are produced by adult female worms in mesenteries of infected hosts. Eggs can cross the intestinal barrier and form granulomas in the tissue or breach and exit the host through fecal excretion. These interactions may affect the host microbiome assemblages. Given the potential for schistosomal alteration of host gut microbiome and subsequent effects on the fecal bacterial composition, it is important to conduct controlled microbiome studies on model animals. While pursuing these studies, it is important to take into account the different conditions in which microbiome studies are conducted and their consequent impacts on variability and reproducibility of results. In particular, we are interested in inter-institutional effects on controlled microbiome studies, in which the study location itself may impact study outcomes. In this work, we report global changes caused by acute and chronic schistosomiasis on the fecal microbiome of mice at two different institutions and three timepoints.
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