Evidence map›Paper›PMID 40445561›Full record

ReviewDiscover oncology2025

Advance in prostate cancer biomarker discovery: bridging detection, prognosis and therapeutics.

Subhayan Das, Shayeri Chatterjee Ganguly, Shiuli Bera, Moumita Kundu

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Subhayan DasDepartment of Allied Health Sciences, Brainware University, Kolkata, West Bengal, India.
Shayeri Chatterjee GangulyDepartment of Pharmaceutical Technology, Brainware University, Kolkata, West Bengal, India.
Shiuli BeraDepartment of Pharmaceutical Technology, Brainware University, Kolkata, West Bengal, India.
Moumita KunduDepartment of Pharmaceutical Technology, Brainware University, Kolkata, West Bengal, India. moumitakundu1991@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the second leading malignancy in males. Prostate cancer can be easily curable if it is diagnosed at an early stage. The prognosis of patients with metastatic or resistant cases can also be improved if adequately characterized with biomarkers. Prognostic and predictive biomarkers are crucial for the prediction of therapeutic response of prostate cancer patients. This article discusses various diagnostic, predictive, and prognostic biomarkers for this cancer. It also highlights the limitations of existing biomarkers and the challenges in novel biomarker discovery for prostate cancer. Moreover, this article emphasizes the application of genomics and epigenomics to discover novel prostate cancer biomarkers. Recent research to explore potential biomarkers for this disease has been reviewed here. Understanding the tumor immune microenvironment is vital for adequately diagnosing tumor tissues and predicting prognosis and therapeutic outcomes. Immune checkpoint markers are also discussed here. The current status of tumor microenvironment-based research for biomarker discovery has been explained in this article, highlighting its potential for novel biomarkers that can be employed in clinical settings.

Indexed as

BiomarkersDiagnosisPrognosisProstate cancerTherapeutics

Identifiers

PMID40445561
PMCPMC12125430

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.