Evidence map›Paper›PMID 40445529›Full record

SynthesisCardiovascular intervention and therapeutics2025

Comparison between robot-assisted and manual percutaneous coronary intervention - an updated systematic review, meta-analysis, propensity-matched investigation, and trial sequential analysis.

Paweł Łajczak, Ayesha Ayesha, Oguz Kagan Sahin, Priscilla Isabel Freeman, Mir Wajid Majeed, Bruno Branco Righetto, Ogechukwu Obi, Gabriel Jacob Moreno, Mrinal Murali Krishna, Kangwa Francis Mulenga and 4 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Cardiovascular intervention and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Paweł ŁajczakMedical University of Silesia, Katowice, Poland. Pawel.lajczak03@outlook.com.ORCID http://orcid.org/0000-0003-0281-5417
Ayesha AyeshaShifa College of Medicine, Islamabad, Pakistan.
Oguz Kagan SahinEdremit State Hospital, Balikesir, Turkey.
Priscilla Isabel FreemanFacultad de Ciencias de la Salud, Programa: Medicina, Universidad del Tolima, Ibague, Colombia.
Mir Wajid MajeedGovernment Medical College, Srinagar, India.
Bruno Branco RighettoUniversity Positivo, Curitiba, Brazil.
Ogechukwu ObiNew York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY, USA.
Gabriel Jacob MorenoCentro Universitário Unidompedro Afya, Salvador, Brazil.
Mrinal Murali KrishnaMedical College Thiruvananthapuram, Thiruvananthapuram, India.
Kangwa Francis MulengaAzerbaijan Medical University, Baku, Azerbaijan.
Emma Ann FinneganSchool of Medicine, Trinity College Dublin, Dublin, Ireland.
Meghna JosephMedical College Thiruvananthapuram, Thiruvananthapuram, India.
Anna ŁajczakMedical University of Silesia, Katowice, Poland.
Michele SchincariolKlinikum Fürth, Friedrich-Alexander-University Erlangen- Nürnberg, Fürth, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Robotic-assistance in the percutaneous coronary intervention procedures (R-PCI) has emerged as a novel alternative to manual PCI (M-PCI). However, previous reviews have not incorporated advancements in new devices. Therefore, we aim to present updated results for a comprehensive systematic review and meta-analysis comparing these two modalities.We systematically searched five databases. Clinical studies comparing R-PCI to M-PCI were included. Continuous outcomes were analyzed using a mean difference (MD), while binary outcomes were assessed with odds ratios (ORs) using random-effect models due to anticipated heterogeneity. A total of 10 papers were included. Clinical success for < 20% residual stenosis was higher (OR 7.93 (95% CI 1.02 to 61.68)), while air kerma was lower (MD - 468.61 (95% CI - 718.32 to - 218.90)) in R-PCI procedures. However, procedural time (MD 5.57 (95% CI - 5.69 to 16.84)), fluoroscopy time (MD - 0.30 (95% CI - 2.26 to 1.66)), contrast dose (MD - 6.29 (95% CI - 25.23 to 12.65)), dose area product (MD - 642.57 (95% CI - 2434.20 to 1149.07)), MACE events (OR 0.54 (95% CI 0.15 to 1.96)), and mortality (OR 1.86 (95% CI 0.82 to 4.22)) showed no significant difference between interventions. TSA showed true positive result. Our meta-analysis reveals decreased air kerma in robotic versus manual PCI but fewer statistically significant outcomes overall. Results from this study offer a more comprehensive view of existing evidence compared to previous analyses.

Indexed as

Coronary Artery DiseasePercutaneous Coronary InterventionRobotic Surgical ProceduresHumansPropensity ScoreMeta-analysisPCIRadiationRobotSafetyTrial sequential analysis

Identifiers

PMID40445529
PMCPMC12167305

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.