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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Commentary on "Predictors of survival among head and neck cancer patients after radiotherapy based on health-related quality of life indices and symptoms-specific outcomes: a systematic review".

Efsun Somay, Erkan Topkan, Ugur Selek

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Efsun SomayDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Baskent University, 82. Street No: 26, Bahcelievler, Ankara, Turkey. efsuner@gmail.com.ORCID http://orcid.org/0000-0001-8251-6913
Erkan TopkanDepartment of Radiation Oncology, Faculty of Medicine, Baskent University, Adana, Turkey.ORCID http://orcid.org/0000-0001-8120-7123
Ugur SelekDepartment of Radiation Oncology, School of Medicine, Koc University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8087-3140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We read with great interest the systematic review by Ghazali et al., which rigorously synthesizes data from 32 longitudinal studies involving 12,206 patients to explore the prognostic significance of health-related quality of life (HRQoL) and symptom-specific outcomes in patients with head and neck cancer (HNC) undergoing radiotherapy (RT). The authors employed best-evidence synthesis methodology and highlighted post-treatment physical function as a robust predictor of overall survival (OS). Moreover, the study underscores the prognostic impact of several clinical variables, such as dysphagia, social eating challenges, and loss of appetite, all of which merit further attention in designing personalized treatment approaches for HNC survivors. While the review makes a timely and essential contribution to the literature, we respectfully suggest several areas where further clarification and expanded analysis may strengthen the interpretation and future applicability of the findings.

Indexed as

Head and Neck NeoplasmsQuality of LifeHumansPrognosisSystematic Reviews as TopicHead and neck cancerQuality of lifeSurveySurvival

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.