Evidence map›Paper›PMID 40445482›Full record

ArticleMolecular neurobiology2025

Whole-Brain Monosynaptic Inputs to Parasubthalamic Calretinin Neurons in Mice.

Han Guo, Mutian Zhang, Jie Huang, Haifeng Zhou, Min Zhang, Hongdan Wang, Xudong Xu, Xiaoyan Liu, Weimin Qu, Zhili Huang

Abstract read
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In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Han Guo *School of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science and Institutes of Brain Science, Huadong Hospital, Fudan University, Shanghai, China.
Mutian Zhang *School of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science and Institutes of Brain Science, Huadong Hospital, Fudan University, Shanghai, China.
Jie Huang *Department of Ophthalmology, Eye, Ear, Nose and Throat Hospital, Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, China.
Haifeng ZhouSchool of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science and Institutes of Brain Science, Huadong Hospital, Fudan University, Shanghai, China.
Min ZhangSchool of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science and Institutes of Brain Science, Huadong Hospital, Fudan University, Shanghai, China.
Hongdan WangMedical Genetic Institute of Henan Province, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, China.
Xudong XuDepartment of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China. xudong@fudan.edu.cn.
Xiaoyan LiuSchool of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science and Institutes of Brain Science, Huadong Hospital, Fudan University, Shanghai, China. xiaoyan5156@163.com.
Weimin QuSchool of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science and Institutes of Brain Science, Huadong Hospital, Fudan University, Shanghai, China. quweimin@fudan.edu.cn.
Zhili HuangSchool of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science and Institutes of Brain Science, Huadong Hospital, Fudan University, Shanghai, China. huangzl@fudan.edu.cn.

Funding

Lingang Laboratory & National Key Laboratory of Human Factors Engineering Joint Grant LG-TKN-202203-01Shanghai Geriatric Medicine Clinical Laboratory Open Research Topics SKLCGM202401Shanghai Science and Technology Innovation Action Plan Natural Science Foundation Project 24ZR1421000STI2030-Major Project 2021ZD0203400the National Natural Science Foundation of China 82201641, 82020108014, 82071491, 31871072the Shanghai Municipal Science and Technology Major Project, ZJLab and Shanghai Center for Brain Science and Brain-Inspired Technology 2018SHZDZX01Young Elite Scientists Sponsorship Program by CAST 2023QNRC001
6 · The paper itself

Abstract

The parasubthalamic nucleus (PSTN) plays a crucial role in various physiological functions, including feeding, motivation, thermoregulation, exploration, sleep-wakefulness and cardiovascular system regulation. However, presynaptic partners that modulate PSTN activity are poorly understood. A significant proportion of PSTN neurons express calretinin (CR). This study employed a modified rabies virus method for cell-type-specific retrograde tracing in combination with a Cre/loxP gene-expression strategy to map the monosynaptic inputs to PSTN

Indexed as

BrainCalbindin 2NeuronsSynapsesThalamusAnimalsGABAergic NeuronsMaleMiceMice, Inbred C57BLCalbindin 2Calretinin neuronsMonosynaptic inputParasubthalamic nucleusRabies virusRetrograde tracing

Identifiers

PMID40445482

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.