Evidence map›Paper›PMID 40445472›Full record

ArticleEJNMMI research2025

Biphasic contrast-enhanced [

Eduards Mamlins, Emil Novruzov, Tadashi Watabe, Yuriko Mori, Mardjan Dabir, Katalin Mattes-György, Christina Antke, Jan Henke, Matthias Boschheidgen, Julian Kirchner and 10 more

Abstract read
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Eduards MamlinsDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Emil NovruzovDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany. Emil.Novruzov@med.uni-duesseldorf.de.ORCID http://orcid.org/0000-0003-1914-1332
Tadashi WatabeInstitute for Radiation Sciences, Osaka University, Osaka, 565-0871, Japan.
Yuriko MoriDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Mardjan DabirDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Katalin Mattes-GyörgyDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Christina AntkeDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Jan HenkeDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Matthias BoschheidgenDepartment of Diagnostic and Interventional Radiology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, 40225, Duesseldorf, Germany.
Julian KirchnerDepartment of Diagnostic and Interventional Radiology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, 40225, Duesseldorf, Germany.
Danny JazmatiDepartment of Radiation Oncology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, 40225, Duesseldorf, Germany.
Jan HausmannDepartment of Radiation Oncology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, 40225, Duesseldorf, Germany.
Jan P RadtkeDepartment of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, 40225, Duesseldorf, Germany.
Günter NiegischDepartment of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, 40225, Duesseldorf, Germany.
Jens CardinaleDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Juliane Hörner-RieberDepartment of Radiation Oncology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, 40225, Duesseldorf, Germany.
Peter AlbersDepartment of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, 40225, Duesseldorf, Germany.
Gerald AntochDepartment of Diagnostic and Interventional Radiology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, 40225, Duesseldorf, Germany.
Frederik L GieselDepartment of Nuclear Medicine, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Lars SchimmöllerDepartment of Diagnostic and Interventional Radiology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, 40225, Duesseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe implementation of PSMA imaging in prostate cancer (PC) management has significantly improved the medical care of patients owing to its clinical impact, particularly with respect to biochemical recurrence. However, there is still an unmet clinical need regarding the correct discrimination of equivocal, centrally located, focal [

resultsThis study investigated a total of 24 biologically male patients with BCR, with a mean PSA level of 0.96 ng/ml at the time of recurrence. The presence of local relapse was regarded as consistent by biphasic, contrast-enhanced [

conclusionsGiven the aforementioned, highly specific unmet clinical need for a relatively small ratio of patients with prostate cancer undergoing PSMA imaging, our proposed acquisition protocol mandates a well-balanced preselection of patients. Under this premise, the study results demonstrated that the optimized acquisition protocol with biphasic contrast-enhanced [

Indexed as

[18F]PSMA-1007Biphasic PSMA imagingContrast enhancementLate imagingLocal relapsePSMA imaging

Identifiers

PMID40445472
PMCPMC12125407

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.