ReviewMolecular biology reports2025
Precision exosome engineering for neurological therapeutics: molecular mechanisms and targeted strategies.
Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Recent Advances in the Non-viral Delivery of Genes to Central Nervous System Disorders.Cellular and molecular neurobiology · 2026Review
- Surface-Engineered Precision Nano-Systems for Targeted Treatment of Huntington's Disease: A Review of Recent Advancements.International journal of nanomedicine · 2026Review
- Exosome-based therapeutics in bone regeneration: from fundamental biology to clinical translation.Stem cell research & therapy · 2025Review
- Cutting-Edge Sensor Technologies for Exosome Detection: Reviewing Role of Antibodies and Aptamers.Biosensors · 2025Review
- Exosome engineering for targeted therapy of brain-infecting pathogens: molecular tools, delivery platforms, and translational advances.Frontiers in medical technology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exosomes are nanoscale extracellular vesicles which are essential for intercellular communication. They have shown great promise in the delivery of drugs into the brain. Recent developments in the use of exosomes to treat neurological conditions are reviewed in this article. Further, it also focuses on molecular and genetic changes that improve the therapeutic effectiveness of these exosomes. Receptor-specific targeting, stimulus-responsive exosomes, and hybrid nanovesicle systems are the three main approaches investigated for facilitating exosome transport across the blood-brain barrier (BBB). Exosomal microRNAs (miRNAs) and other bioactive molecules have important roles in the brain, and it emphasizes their potential as biomarkers, therapeutic agents and modulators of disease pathogenesis. Additionally, it addresses how biomimetic and synthetic exosomes can enhance focused medication delivery to the brain. It also covers how these exosomes are involved in reducing systemic adverse effects while providing important information for next-generation neurotherapeutic strategies.
Indexed as
Identifiers
40445446What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.