Evidence map›Paper›PMID 40445392›Full record

ArticleEuropean journal of nutrition2025

Bread, wholegrain consumption and weight change from middle to late adulthood: a prospective cohort study.

Ingrid Revheim, Zoya Sabir, Jutta Dierkes, Anette E Buyken, Rikard Landberg, Inka Alten, Ulrike Spielau, Hanne Rosendahl-Riise

Abstract read
In one paragraph

Article in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ingrid RevheimCentre for Nutrition, Department of Clinical Medicine, University of Bergen, Post box 7804, Bergen, 5020, Norway.
Zoya SabirCentre for Nutrition, Department of Clinical Medicine, University of Bergen, Post box 7804, Bergen, 5020, Norway.
Jutta DierkesCentre for Nutrition, Department of Clinical Medicine, University of Bergen, Post box 7804, Bergen, 5020, Norway.
Anette E BuykenInstitute of Nutrition, Consumption and Health, Faculty of Natural Sciences, Paderborn University, Paderborn, Germany.
Rikard LandbergDivision of Food and Nutrition Science, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.
Inka AltenCentre for Nutrition, Department of Clinical Medicine, University of Bergen, Post box 7804, Bergen, 5020, Norway.
Ulrike SpielauCentre for Nutrition, Department of Clinical Medicine, University of Bergen, Post box 7804, Bergen, 5020, Norway.
Hanne Rosendahl-RiiseCentre for Nutrition, Department of Clinical Medicine, University of Bergen, Post box 7804, Bergen, 5020, Norway. Hanne.rosendahl-riise@uib.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBread is a global staple with large variations in carbohydrate quality. The role of bread for weight regulation has been controversial and few studies have investigated associations of bread consumption with long-term weight changes. Therefore, our objective was to investigate the associations of baseline intake of bread, different types of bread, and whole grains as well as plasma alkylresorcinol - a biomarker of wholegrain wheat and rye intake - with weight changes during a follow-up covering the 6th and 7th decades of life.

methodsThe current analyses were conducted in 1764 men and women (47.4 ± 0.6 years at baseline) participating in the second and third wave of the Hordaland Health Study. A food frequency questionnaire was used to estimate baseline bread and wholegrain intake. Baseline plasma alkylresorcinol concentrations were determined in blood samples. The outcome was weight change (kg) during the 20-year follow-up. Multivariate linear regression models were applied.

resultsParticipants gained on average 2.1 ± 7.4 kg during follow-up. While total bread intake at baseline was not associated with weight change, a higher white bread intake was associated with weight gain (0.017 kg/g white bread/day, 95% CI: 0.002, 0.032 kg/g white bread/day). Wholegrain consumption - but not wholegrain bread - was inversely associated with weight gain (-0.013 kg/g whole grain/day, 95% CI: -0.026, 0.000 kg/g whole grain/day). Accordingly, plasma alkylresorcinols were inversely associated with weight gain (-0.004 kg/nmol/L alkylresorcinol, 95% CI: -0.007, -0.002 kg/nmol/L alkylresorcinol).

conclusionThe current study suggests that weight regulation is associated with the carbohydrate quality of breads, i.e., refined versus wholegrain breads. Wholegrain intake, based on both self-reported dietary data and objective biomarkers, may improve weight regulation from middle to late adulthood.

Indexed as

BreadDietWeight GainWhole GrainsBiomarkersFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesResorcinolsSecaleTriticumBiomarkersResorcinolsAlkylresorcinolsBreadEpidemiologyWeight changeWhole grains

Identifiers

PMID40445392
PMCPMC12125146

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.