Evidence map›Paper›PMID 40445368›Full record

ArticleCurrent microbiology2025

Chlorhexidine-Loaded Zinc Nanoparticles: A Potent Antibacterial Agent Against Streptococcus pneumoniae.

Rakesh Kumar, Renu Sharma, Sushila Kaura, Neeraj Sethi, Ikbal Shah, Kumar D Gahlot

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rakesh KumarDepartment of Chemistry, Om Sterling Global University, Hisar, India.
Renu SharmaDepartment of Chemistry, Om Sterling Global University, Hisar, India.
Sushila KauraDepartment of Pharmaceutical Sciences, Om Sterling Global University, Hisar, India.
Neeraj SethiDepartment of Biotechnology, Om Sterling Global University, Hisar, India.
Ikbal ShahDepartment of Microbiology, Om Sterling Global University, Hisar, India.
Kumar D GahlotDepartment of Molecular Biology, Umeå University, Umeå, Sweden. dharmender.kumar.gahlot@umu.se.ORCID http://orcid.org/0000-0001-6963-0009

Funding

Umeå Universitet APC fee
6 · The paper itself

Abstract

Nanoformulations deliver antibacterial agents synergistically. Positively charged Zn nanocomplexes were used as carriers for chlorhexidine (CHX), developed using ionic liquids. The CHX-loaded Zn nanoparticles (CHZNPs) were characterised through various techniques, including UV-visible Spectroscopy, TEM, FTIR, and Zeta potential analysis. The average diameters of ZNPs and CHZNPs were 27.43 and 29.66 nm, respectively. CHZNPs consistently released CHX, enhancing its antibacterial effect. Tests against antibiotic-resistant Streptococcus pneumoniae strain 7465 revealed that CHZNPs significantly reduced bacterial viability. At 100 μg/mL, CHX showed the highest antibacterial activity with the lowest minimal inhibitory concentration (MIC

Indexed as

Anti-Bacterial AgentsChlorhexidineMetal NanoparticlesStreptococcus pneumoniaeZincMicrobial Sensitivity TestsMicrobial ViabilityNanoparticlesAnti-Bacterial AgentsChlorhexidineZinc

Identifiers

PMID40445368
PMCPMC12125063

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.