Evidence map›Paper›PMID 40445361›Full record

ReviewMolecular biology reports2025

Anthocyanin pathway in eggplant: genetic regulation and future directions for metabolic engineering.

Guru Prasad Manickam, Arul L, Sathiyamurthy V A, Vijayalakshmi D, Kumar K K

Abstract readReview
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In one paragraph

Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guru Prasad ManickamDepartment of Plant Biotechnology, CPMB&B, TNAU, Coimbatore, India.ORCID http://orcid.org/0009-0004-7694-7708
Arul LDepartment of Plant Biotechnology, CPMB&B, TNAU, Coimbatore, India.ORCID http://orcid.org/0000-0001-9706-5975
Sathiyamurthy V ADepartment of Vegetable Science, TNAU, Coimbatore, India.ORCID http://orcid.org/0000-0001-7838-505X
Vijayalakshmi DDepartment of Plant Physiology, TNAU, Coimbatore, India.ORCID http://orcid.org/0000-0002-8292-2548
Kumar K KDepartment of Plant Biotechnology, CPMB&B, TNAU, Coimbatore, India. kumarbiotech@gmail.com.ORCID http://orcid.org/0000-0002-9827-2295

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthocyanins are flavonoids and play a key role in eggplant color, nutritional value, and stress tolerance. Their biosynthesis is tightly regulated through a complex interplay of structural and regulatory genes, primarily by the MYB-bHLH-WD40 (MBW) transcriptional complex. Environmental factors like light, temperature, and abiotic stress regulate anthocyanin accumulation. Different types of anthocyanins accumulate in different eggplant tissues depending on genetic and environmental factors. The intracellular transport and accumulation of anthocyanins rely on specific membrane transporters, which sequester anthocyanins into vacuoles. Recent advances in genetic and metabolic engineering have created novel opportunities for targeted gene editing, overexpression of key transcription factors, and optimization of metabolic pathways to enhance the anthocyanin content of eggplant. This review describes the molecular mechanisms that regulate anthocyanin biosynthesis, transport mechanisms, and accumulation patterns of anthocyanins, as well as the role of regulatory networks and biotechnological strategies that can be adopted to enhance anthocyanin levels for improved nutritional and commercial value.

Indexed as

AnthocyaninsMetabolic EngineeringSolanum melongenaGene Expression Regulation, PlantPlant ProteinsPlants, Genetically ModifiedAnthocyaninsPlant ProteinsAnthocyaninBiosynthesisMBW complexRegulatory genesStructural genes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.