Evidence map›Paper›PMID 40445245›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Radiological evaluation of posterior cervical misalignment by ligamentum flavum angle in patients with degenerative cervical myelopathy.

Junhua Ye, Ramzi Roshani, Qinguo Huang, Dongying Zheng, Qiang Zhou, Hong Li, Lin Peng, Songtao Qi, Yuntao Lu

Abstract read
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junhua Ye *Department of Neurosurgery, Meizhou People's Hospital (Huangtang Hospital), Meizhou, 514000, China.
Ramzi Roshani *Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qinguo Huang *Department of Neurosurgery, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Dongying ZhengDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qiang ZhouDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Hong LiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Lin PengDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Songtao QiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuntao LuDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China. lllu2000yun@gmail.com.ORCID 0000-0003-4125-304X

Funding

National High Level Hospital Clinical Research Funding 2022-PUMCH-D-004National Key Clinical Specialty Project, the Clinical Research Program of Nanfang Hospital, Southern medical University 2021CR018National Natural Science Foundation of China 81972355National Natural Science Foundation of China 82373398National Natural Science Foundation of Guangdong Province 2019B151502048
6 · The paper itself

Abstract

purposePosterior cervical misalignment is commonly observed in patients with degenerative cervical myelopathy (DCM), yet its clinical significance remains unclear. This study takes aim to investigate the radiological value of ligamentum flavum angle (LFA) to evaluate the implications of posterior cervical misalignment in DCM.

methodsBaseline LFA was determined in 76 adults with normal cervical alignment. LFA was then analyzed in 155 DCM patients and categorized into enlarging (eLFA), normal (nLFA), and decreasing LFA (dLFA) groups. Cervical spine parameters and MRI findings were compared, and multiple linear regression identified factors associated with LFA changes. Static LFA on MRI and dynamic LFA (ΔLFA) on X-ray were evaluated for detecting cervical instability.

resultsThe mean LFA in normal subjects (C2/3 to C6/7) was 76.3 ± 7.2°, varying by segment and age. The LFA was significantly reduced in DCM patients (70.7 ± 11.6°). The spinal cord diameter of the adjacent vertebrae and the increased signal intensity were significant difference among eLFA, nLFA and dLFA groups. LFA correlated with vertebral body movement (β = - 3.361, P < 0.001) and cervical disc angle (β = - 0.774, P < 0.001). The static LFA cutoff for posterior slippage was 67.6°, and △LFA for instability was 12.3°.

conclusionsPosterior cervical spine misalignment in DCM is closely linked to both horizontal and angular vertebral displacements, potentially exacerbating spinal cord injury. Static and dynamic LFA measurements provide valuable supplementary parameters for the accurate assessment of cervical instability.

Indexed as

Cervical VertebraeLigamentum FlavumMagnetic Resonance ImagingSpinal Cord DiseasesAdultCase-Control StudiesClinical RelevanceFemaleHumansJoint DislocationsJoint InstabilityLinear ModelsMaleMiddle AgedCervical instabilityDegenerative cervical myelopathyLigamentum flavum anglePosterior cervical spine misalignmentVertebral displacement

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.