Evidence map›Paper›PMID 40445232›Full record

ArticleAntonie van Leeuwenhoek2025

Effects of DpWRI1-like gene overexpression in transgenic Dunaliella parva.

Lingru Ruan, Juying Lin, Lina Wu, Yanyan Liang, Xiumin Zhang, Shiyu Liang, Limei Huang, Changhua Shang

Abstract read
PubMed Publisher
In one paragraph

Article in Antonie van Leeuwenhoek, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effects of DpTF Gene Overexpression on Dunaliella parva.Applied biochemistry and biotechnology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lingru Ruan *Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China.
Juying Lin *Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China.
Lina WuKey Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China.
Yanyan LiangKey Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China.
Xiumin ZhangKey Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China.
Shiyu LiangKey Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China.
Limei HuangKey Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China.
Changhua ShangKey Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education and Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin (Guangxi Normal University) and University Engineering Research Center of Bioinformation and Genetic Improvement of Specialty Crops, Guilin, 541006, Guangxi, China. shangchanghua@mailbox.gxnu.edu.cn.

Funding

2024 Joint Fund for Guangxi Normal University and National Natural Science Foundation of China 2024PY020Guangxi Key Research and Development Program 2023AB01132Natural Science Foundation of Guangxi Zhuang Autonomous Region 2024JJA130020
6 · The paper itself

Abstract

WRINKLED1 (WRI1) is a transcription factor (TF) of the APETALA2 (AP2) family, which regulates oil synthesis in plants. Dunaliella parva is a microalga, which attracts widespread attention due to its strong resistance to unfavorable environments and simple cultivation conditions. In our earlier study, DpWRI1-like was identified but the role of WRI1 for oil accumulation remains unclear in D. parva. Therefore, in this study, the effects of DpWRI1-like overexpression on D. parva were evaluated. Overexpressing DpWRI1-like could greatly increase the amount of oil while decreasing the amount of starch in transgenic D. parva. In addition, mRNA levels of many genes (ACC, GPAT and DGAT) related to fatty acid synthesis/triacylglycerol (TAG) synthesis increased in transgenic D. parva. In conclusion, the DpWRI1-like protein could convert carbon flow to the biosynthesis of fatty acids and triacylglycerol (TAG).

Indexed as

ChlorophyceaeMicroalgaePlant ProteinsTranscription FactorsFatty AcidsGene Expression Regulation, PlantPlants, Genetically ModifiedStarchTriglyceridesFatty AcidsPlant ProteinsStarchTranscription FactorsTriglyceridesDpWRI1-likeDunaliella parvaOil biosynthesisTranscription factor

Identifiers

PMID40445232

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.