Evidence map›Paper›PMID 40445078›Full record

ArticleBrazilian journal of cardiovascular surgery2025

Del Nido vs. Blood Cardioplegia: A Comparative Analysis of Postoperative Atrial Fibrillation in Coronary Artery Bypass Grafting Patients.

Hasan Toz, Ali Aycan Kavala, Saygın Türkyılmaz, Yusuf Kuserli, Gülsüm Türkyılmaz, Mehmet Ali Yesiltas, Necdet Kılıçaslan

Abstract readComparative Study
In one paragraph

Article in Brazilian journal of cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hasan TozDepartment of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
Ali Aycan KavalaDepartment of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
Saygın TürkyılmazDepartment of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
Yusuf KuserliDepartment of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
Gülsüm TürkyılmazDepartment of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
Mehmet Ali YesiltasDepartment of Cardiovascular Surgery, ISTUN Sisli Kolan International Hospital, Istanbul, Turkey.ORCID 0000-0002-5208-0626
Necdet KılıçaslanDepartment of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCardioplegia solution, also called the del Nido solution, has been widely used in pediatric cardiac surgeries, and has recently started to be used in adult cardiac surgeries. In this context, this study aimed to investigate the relationship between the use of del Nido and blood cardioplegia solutions and postoperative atrial fibrillation rates in our clinic.

methodsThe study sample comprised 140 patients who underwent coronary artery bypass grafting. The del Nido and blood cardioplegia solutions were used in 70 (50%) patients. The postoperative atrial fibrillation rates of both groups were compared. Additionally, patients' preoperative, intraoperative, and postoperative data were evaluated.

resultsThe cardiopulmonary bypass duration and defibrillation rate were lower in the del Nido cardioplegia group than in the blood cardioplegia group (P < 0.001). Atrial fibrillation rates on postoperative days one, five, and 30 were significantly lower in the del Nido cardioplegia group than in the blood cardioplegia group (P < 0.001, P < 0.001, and P = 0.007, respectively).

conclusionThe postoperative atrial fibrillation rate was significantly lower in the del Nido cardioplegia group than in the blood cardioplegia group. In addition, the del Nido cardioplegia solution did not interrupt the surgical flow, thus resulting in less total perfusion, shorter cross-clamping durations, and fewer defibrillation needs. In conclusion, the del Nido cardioplegia solution can be used safely and effectively in coronary artery bypass grafting surgeries.

Indexed as

Atrial FibrillationCardioplegic SolutionsCoronary Artery BypassHeart Arrest, InducedPostoperative ComplicationsAgedCalcium ChlorideCardiopulmonary BypassElectrolytesFemaleGlucoseHumansLidocaineMagnesium SulfateMaleMannitolCalcium ChlorideCardioplegic SolutionsDel Nido cardioplegia solutionElectrolytesGlucoseLidocaineMagnesium SulfateMannitolPotassium ChlorideSodium BicarbonateSolutionsAtrial FibrillationCardioplegia SolutionCardiopulmonary BypassDel Nido cardioplegia solutionPerfusion.

Identifiers

PMID40445078
PMCPMC12131428

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.