Evidence map›Paper›PMID 40444982›Full record

ArticleApplied and environmental microbiology2025

Genome-wide investigation of outer membrane protein families under mosaic evolution in

Xin Cao, Cuihua Cao, Zefan Chen, Jialin Li, Zikun Yao, Yidong Zheng, Jinjin Wu, Zeling Li, Yueming Hu, Gaofeng Hao and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xin Cao *Youth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Cuihua Cao *Youth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Zefan Chen *Youth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Jialin LiYouth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Zikun YaoYouth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Yidong ZhengYouth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Jinjin WuYouth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Zeling LiYouth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.
Yueming HuDepartment of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
Gaofeng HaoDepartment of Stomatology, Shenzhen Maternal and Child Health Care Hospital Affiliated to Southern Medical University, Shenzhen, China.
Guoqiang ZhuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.
Wolfgang KösterVaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada.
Aaron P WhiteVaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada.ORCID 0000-0003-2746-5265
Yejun WangYouth Innovation Team of Medical Bioinformatics, Shenzhen University Medical School, Shenzhen, Guangdong, China.ORCID 0000-0003-4030-0027

Funding

Natural Science Fund of Shenzhen JCYJ20190808165205582Undergraduate Training Programs for Innovation and Entrepreneurship of Guandong Province S202410590108, S202410590107
6 · The paper itself

Abstract

Several genes in Gram-negative bacteria encoding outer membrane proteins (OMPs) have been reported to show patterns of mosaic evolution featured by a mixture of negative selection and local recombination. Here, we improved a strategy and applied it to screen OMPs under mosaic evolution in

Indexed as

Bacterial Outer Membrane ProteinsEscherichia coliEscherichia coli ProteinsEvolution, MolecularGenome, BacterialBacterial Outer Membrane ProteinsEscherichia coli ProteinsEscherichia colihighly variable region (HVR)mosaic evolutionouter membrane protein (OMP)positive selection

Identifiers

PMID40444982
PMCPMC12175518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.