Evidence map›Paper›PMID 40444879›Full record

ArticleMolecular pain

Nanoparticulate MgH

Hang Xu, Hongtao Lu, Lu Lu, Zhenghao Li, Zhisheng Piao, Yi Jia, Xiaoyan Meng, Feixiang Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hang XuDepartment of Critical Care Medicine, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, China.
Hongtao LuDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Lu LuDepartment of Critical Care Medicine, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, China.
Zhenghao LiInstitute of Neuroscience and Key Laboratory of Molecular Neurobiology of Military of Education, Naval Medical University, Shanghai, China.
Zhisheng PiaoDepartment of Critical Care Medicine, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, China.
Yi JiaDepartment of Critical Care Medicine, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, China.
Xiaoyan MengDepartment of Critical Care Medicine, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, China.
Feixiang WuDepartment of Critical Care Medicine, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, China.ORCID 0009-0001-3040-7675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBone cancer metastases are the third most common site of cancer spread after lungs and liver. This condition often causes severe pain that impairs patients' physical, psychological, and social well-being. We aimed to explore the potential therapeutic benefits of magnesium hydride (MgH

methodsA BCP model was established in Wistar rats. Daily oral dosing of 0.5% w/w MgH

resultsMgH

conclusionMgH

Indexed as

Bone NeoplasmsCancer PainInflammasomesNanoparticlesNLR Family, Pyrin Domain-Containing 3 ProteinTRPM Cation ChannelsAnimalsHippocampusMaleMicrogliaRatsRats, WistarInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, ratTrpm2 protein, ratTRPM Cation Channelsbone cancer painNanoparticulate MgH2NLRP3 inflammasomeTRPM2

Identifiers

PMID40444879
PMCPMC12185947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.