ArticleEarly intervention in psychiatry2025
Exploring Behavioural Patterns in Youth Predisposed to Bipolar Disorder and the Role of Interpersonal Trauma Using the Adolescent Brain Cognitive Development (ABCD) Dataset.
Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Childhood Maltreatment in the Context of Familial Bipolar I Disorder Risk Predicts Major Depressive Disorder in Adolescents.JAACAP open · 2026Article
- Interpersonal trauma exposure is associated with cognitive disengagement syndrome symptoms in early adolescents.European child & adolescent psychiatry · 2026Article
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Authors and funding
4 authors.
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Abstract
introductionBipolar disorder (BD) is a severe, persistent disorder that causes functional impairment. Besides heritability, environmental factors, such as traumatic experience, impact the development of BD. Little is known about the early developmental signs of this disorder; therefore, this study aims to look at the impact of interpersonal trauma on the early developmental signs of BD. Specifically, differences in psychopathological behaviours were investigated between (1) at-risk children and controls and (2) at-risk children who experienced an interpersonal traumatic event and those who did not.
methodsUsing the Adolescent Brain Cognitive Development (ABCD) dataset, participants with a first-degree relative with BD were identified (N
resultsCompared to controls, at-risk children exhibited a significantly greater number of manic symptoms at baseline and 2-year follow-up, and anxiety symptoms at follow-up. No significant differences were found between the trauma and no-trauma groups at either baseline or follow-up. DISCUSSION: These results confirm the presence of early symptoms in at-risk children, in line with the staging model of BD. Extended longitudinal research is needed to further investigate the potential specific role of trauma on its early behavioural patterns.
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