ArticleEpigenomics2025
SNP-associated differential methylation in
Article in Epigenomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveAssociations have been seen between suicide and differential DNA methylation, with one study showing significant hypomethylation of
methodWith pyrosequencing, we looked at the previously identified region of interest in
resultsNone of the CpG sites measured had an association between groups, although there were distinct clusters of differential methylation in each group. Applying genotypes of SNPs found in the region of interest, rs2121558 and rs1447093, these clusters showed stepwise methylation at each CpG site, regardless of phenotype.
conclusionsIn this small sample size study, differential methylation in
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