ReviewCurrent diabetes reviews2026
An Overview and Review of Growth Factors in Wound Healing: Emerging Trends and Innovations.
Review in Current diabetes reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Formulation Attributes and Preclinical Wound Healing Outcomes of Natural Product Based Nanoemulsions: A Systematic Review.International journal of nanomedicine · 2026Pooled it
- [Effect of concentrated growth factors in guided tissue regeneration for the treatment of mandibular molar furcation lesions].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Trial
- Article
- Review
- Probiotics and Extracellular Vesicles as Redox Modulators in Wound Healing: From Microbial Therapeutics to Engineered Nanotherapeutic Strategies.Antioxidants (Basel, Switzerland) · 2026Review
- Multifunctional Electrospun PCL/Starch/n-AlInternational journal of molecular sciences · 2026Article
- Phytochemical Profiling and Computational Screening ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Unveiling the Mysteries of CLEC3B: Physiological Roles, Pathological Impacts, and Research Gaps.Cells · 2026Review
- Review
- Orthobiologics in Trauma: Current Trends, Future Directions, and Regenerative Strategies.Cureus · 2026Review
- Beyond Platelet Count: Rethinking Platelet-Rich Plasma Efficacy Through Growth Factor Biology and Functional Quality.Life (Basel, Switzerland) · 2026Review
- Lung microbial dysregulation and TNF inhibition are associated with worsened nontuberculous mycobacterial lung disease.Frontiers in microbiology · 2026Article
- Peripheral blood cytokines during early and post-acute stages of SARS-CoV-2 infection are associated with disease severity and long-term symptoms.Frontiers in immunology · 2026Article
- Transforming PRP into a shelf-stable therapy: Lyophilization preserves angiogenic and regenerative properties.Iranian journal of basic medical sciences · 2026Article
- Review
- Platelet count correlates with systemic inflammation but not with synovial vascularity in rheumatoid and psoriatic arthritis: a cross-sectional ultrasound-based study.Rheumatology international · 2025Article
- Microbial Biofilms as Barriers to Chronic Wound Healing: Diagnostic Challenges and Therapeutic Advances.Journal of clinical medicine · 2025Review
- Active Peptides Derived from Snail Mucus Promoted Wound Healing by Enhancing Endothelial Cell Proliferation and Angiogenesis.International journal of molecular sciences · 2025Article
- Bioengineered Skin from a Platelet-Derived Hydrogel Repairs Full Thickness Wounds in a Pre-Clinical Mouse Model.International journal of molecular sciences · 2025Article
- Cellular Senescence in Skin Wound Repair: Dual Roles and Senotherapeutic Interventions.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing is a complex process involving various cellular and molecular events aimed at restoring tissue integrity. Growth factors play a pivotal role in orchestrating these events by regulating cell migration, proliferation, differentiation, and extracellular matrix synthesis. Several growth factors have been identified as crucial mediators of wound healing, including PDGF, TGF-β, VEGF, FGF, and EGF. PDGF is released by platelets upon injury and stimulates the migration and proliferation of fibroblasts and smooth muscle cells, promoting the formation of granulation tissue. TGF-β regulates various aspects of wound healing, including inflammation, collagen deposition, and tissue remodeling. VEGF promotes angiogenesis, facilitating the formation of new blood vessels to supply oxygen and nutrients to the healing tissue. FGF stimulates fibroblast proliferation and angiogenesis, contributing to tissue regeneration. EGF promotes the migration and proliferation of epithelial cells, aiding in the re-epithelialization of the wound. These growth factors act in a coordinated manner to promote each phase of wound healing, including hemostasis, inflammation, proliferation, and remodeling. Dysregulation of growth factor expression or signaling can impair the healing process, leading to chronic wounds or excessive scar formation. Understanding the roles of growth factors in wound healing has led to the development of therapeutic strategies aimed at enhancing wound repair.
Indexed as
Identifiers
40444617What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.