Evidence map›Paper›PMID 40444373›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

Coxsackievirus B4 (CV-B4) linked to four severe neonatal infections including one fatal, Northern Ireland, October 2024 to February 2025.

Susan A Feeney, Marie Clare Crilly, Sharon Christie, Julie Lewis, Anne Eilis McColgan, Marc Niebel, James P McKenna

Abstract readCase Reports
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susan A FeeneyRegional Virus Laboratory, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom.
Marie Clare CrillyRegional Virus Laboratory, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom.
Sharon ChristiePaediatric Infectious Disease, Royal Belfast Hospital for Sick Children, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom.
Julie LewisPaediatric Unit, Southern Health and Social Care Trust, Belfast, Northern Ireland, United Kingdom.
Anne Eilis McColganRegional Virus Laboratory, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom.
Marc NiebelRegional Virus Laboratory, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom.
James P McKennaRegional Virus Laboratory, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report four cases of severe neonatal non-polio enterovirus infection, requiring hospital admission. Infants presented to different regional hospitals across Northern Ireland from late 2024 to early 2025. Three had neonatal meningitis and one showed rapid demise, leading to sepsis, multi-organ failure and death at day 6 of life. All infants were less than 18 days old at presentation, two were considered congenital infections, with one presenting symptoms at birth. All infants had detectable enterovirus RNA, typed as coxsackievirus B4.

Indexed as

Coxsackievirus InfectionsEnterovirus B, HumanMeningitis, ViralFatal OutcomeFemaleHumansInfantInfant, NewbornMaleMultiple Organ FailureNorthern IrelandRNA, ViralSepsisRNA, ViralcoagulopathycongenitalCoxsackievirus B4CV-B4Enterovirusenterovirus meningitisneonatal sepsisnotifiable

Identifiers

PMID40444373
PMCPMC12124110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.