Evidence map›Paper›PMID 40444287›Full record

ArticlePeerJ2025

Development and validation of an in-hospital major adverse cardiovascular events risk model for young patients with acute coronary syndrome: a retrospective cohort study.

Jia Zheng, Junyang Li, Tingting Li, Fang Hu, Degang Cheng, Chengzhi Lu

Abstract readValidation Study
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia ZhengDepartment of Cardiology, Tianjin First Central Hospital, Tianjin, China.
Junyang LiDepartment of Neurosurgery, Chinese People's Liberation General Hospital, Beijing, China.
Tingting LiDepartment of Respiratory and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Fang HuDepartment of Cardiology, Tianjin First Central Hospital, Tianjin, China.
Degang ChengDepartment of Cardiology, Tianjin First Central Hospital, Tianjin, China.
Chengzhi LuDepartment of Cardiology, Tianjin First Central Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of acute coronary syndrome (ACS) among young individuals is increasing, making it a leading cause of mortality in this population. This study aimed to develop and validate a risk prediction model for in-hospital major adverse cardiovascular events (MACE) in young ACS patients. Methods: A retrospective analysis was performed to predict in-hospital MACE. Patients were divided into a training set ( Results: White blood cell count, Killip classification, lymphocyte count, heart rate, triglycerides, and Gensini score were identified as significant predictors. The constructed nomogram demonstrated strong predictive performance. The area under the ROC curve (AUC) was 0.9242 (95% confidence interval [CI]: [0.8841-0.9643]) for the training set and 0.8346 (95% CI [0.742-0.9272]) for the testing set, with respective cut-off values of 0.107 and 0.119. Calibration was confirmed with Hosmer-Lemeshow statistics of 12.454 ( Conclusions: The proposed nomogram model demonstrated robust discrimination and calibration, offering a valuable tool for predicting the risk of in-hospital MACE in young ACS patients.

Indexed as

Acute Coronary SyndromeAdultFemaleHumansMaleMiddle AgedNomogramsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveAcute coronary syndromeMajor adverse cardiovascular eventsNomogramPredictive modelYoung patients

Identifiers

PMID40444287
PMCPMC12121619

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.