Evidence map›Paper›PMID 40444256›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2024

Feature Extraction for Generative Medical Imaging Evaluation: New Evidence Against an Evolving Trend.

McKell Woodland, Austin Castelo, Mais Al Taie, Jessica Albuquerque Marques Silva, Mohamed Eltaher, Frank Mohn, Alexander Shieh, Suprateek Kundu, Joshua P Yung, Ankit B Patel and 1 more

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. DJournal of imaging · 2026
    Article
  3. Article
  4. Generating Novel Brain Morphology by Deforming Learned Templates.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

McKell WoodlandThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0000-0003-0995-3695
Austin CasteloThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0009-0009-3015-3570
Mais Al TaieThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0009-0000-9298-6644
Jessica Albuquerque Marques SilvaThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0000-0003-0616-982X
Mohamed EltaherThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0009-0008-2078-4718
Frank MohnThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0009-0001-9264-9725
Alexander ShiehThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0009-0005-7450-2702
Suprateek KunduThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0000-0002-1767-4875
Joshua P YungThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0000-0003-3752-5997
Ankit B PatelRice University, Houston TX 77005, USA.ORCID 0000-0001-9678-496X
Kristy K BrockThe University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.ORCID 0000-0001-9364-5040

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Image Guided Cancer Therapy Training ProgramT32CA261856 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Kristy Brock, Clifton David Fuller · 2022 to 2026
$1.2M
NCI NIH HHS P30 CA016672NCI NIH HHS T32 CA261856
6 · The paper itself

Abstract

Fréchet Inception Distance (FID) is a widely used metric for assessing synthetic image quality. It relies on an ImageNet-based feature extractor, making its applicability to medical imaging unclear. A recent trend is to adapt FID to medical imaging through feature extractors trained on medical images. Our study challenges this practice by demonstrating that ImageNet-based extractors are more consistent and aligned with human judgment than their RadImageNet counterparts. We evaluated sixteen StyleGAN2 networks across four medical imaging modalities and four data augmentation techniques with Fréchet distances (FDs) computed using eleven ImageNet or RadImageNet-trained feature extractors. Comparison with human judgment via visual Turing tests revealed that ImageNet-based extractors produced rankings consistent with human judgment, with the FD derived from the ImageNet-trained SwAV extractor significantly correlating with expert evaluations. In contrast, RadImageNet-based rankings were volatile and inconsistent with human judgment. Our findings challenge prevailing assumptions, providing novel evidence that medical image-trained feature extractors do not inherently improve FDs and can even compromise their reliability. Our code is available at https://github.com/mckellwoodland/fid-med-eval.

Indexed as

Fréchet Inception DistanceGenerative Medical Imaging

Identifiers

PMID40444256
PMCPMC12117514

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.