Evidence map›Paper›PMID 40444239›Full record

ArticleFrontiers in endocrinology2025

Study on medication adherence in patients with gestational diabetes mellitus complicated by postpartum glucose metabolism disorders based on the risk perception attitude framework.

Bing Zhou, Zhuolin Zhou, Yu Sun, Ting He, Weihong Ge, Lingjun Sun, Cheng Ji

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Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Bing Zhou *Department of Pharmacy, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
Zhuolin Zhou *Department of Pharmacy, China Pharmaceutical University Nanjing Drum Tower Hospital, Nanjing, China.
Yu Sun *Department of Pharmacy, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
Ting HeDepartment of Pharmacy, China Pharmaceutical University Nanjing Drum Tower Hospital, Nanjing, China.
Weihong GeDepartment of Pharmacy, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
Lingjun SunDepartment of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Cheng JiDepartment of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to assess the compliance with anti-hypoglycemic drugs among postpartum patients with gestational diabetes mellitus (GDM) through a questionnaire survey, and to examine the factors that may influence this adherence. The goal is to enhance pharmacists' medication practices and improve glycemic control. Method: Based on the theory of risk perception attitude framework, the study selected pregnant women who delivered at Nanjing DrumTower Hospital's obstetrics department from 2020 to 2022 and were diagnosed with GDM as the research subjects. The Morisky Medication Adherence Scale was used to evaluate their medication adherence. The correlation matrix was used to express whether there is a correlation between risk perception, self-efficacy, and medication adherence. Finally, a linear hierarchical regression model was used to present the moderating effect of self-efficacy on the relationship between risk perception and medication adherence. Results: A total of 80 postpartum GDM patients receiving medication intervention were included in the study to assess medication adherence. The median score on the MMAS-8 scale was 3.75 (3.50, 5.50). The results of the Spearman test showed a positive correlation between GDM patients' perception of future diabetes risk and postpartum medication adherence (r= 0.778, P<0.001). Additionally, self-efficacy was also positively correlated with medication adherence (r= 0.631, P<0.001). The results of the linear stratified regression model indicated that self-efficacy moderates the relationship between risk perception and medication adherence. Conclusion: The results of the MMAS-8 scale survey indicate poor medication adherence among postpartum GDM patients, with a significantly lower rate of good medication adherence compared to general T2DM patients. The stratified regression analysis demonstrates that risk perception and self-efficacy jointly influence postpartum medication adherence, and the risk perception attitude model can predict medication adherence among GDM patients postpartum.

Indexed as

Diabetes, GestationalHypoglycemic AgentsMedication AdherenceAdultFemaleHumansPerceptionPostpartum PeriodPregnancySelf EfficacySurveys and QuestionnairesHypoglycemic Agentsblood glucose managementgestational diabetes mellitusmedication adherencepostpartum glucose metabolism abnormalitiesrisk perception attitude framework theory

Identifiers

PMID40444239
PMCPMC12119265

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.