Evidence map›Paper›PMID 40444217›Full record

ReviewEuropean heart journal open2025

Decreased peak atrial longitudinal strain and left atrial contraction strain rate values may predict atrial fibrillation in patients in sinus rhythm at baseline: a systematic review and meta-analysis.

Henriette Mészáros, Rita Nagy, Péter Fehérvári, Péter Hegyi, Enikő Pomozi, Zsombor Simon, Andrea Ágnes Molnár, Sándor Nardai, Béla Péter Merkely, Pál Ábrahám

Abstract readReview
In one paragraph

Review in European heart journal open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Henriette MészárosHeart and Vascular Centre of Semmelweis University, Városmajor Street 68, 1122 Budapest, Hungary.
Rita NagyCentre for Translational Medicine, Semmelweis University, Baross Street 22, 1085 Budapest, Hungary.
Péter FehérváriCentre for Translational Medicine, Semmelweis University, Baross Street 22, 1085 Budapest, Hungary.
Péter HegyiCentre for Translational Medicine, Semmelweis University, Baross Street 22, 1085 Budapest, Hungary.
Enikő PomoziHeart and Vascular Centre of Semmelweis University, Városmajor Street 68, 1122 Budapest, Hungary.
Zsombor SimonCentre for Translational Medicine, Semmelweis University, Baross Street 22, 1085 Budapest, Hungary.
Andrea Ágnes MolnárHeart and Vascular Centre of Semmelweis University, Városmajor Street 68, 1122 Budapest, Hungary.
Sándor NardaiHeart and Vascular Centre of Semmelweis University, Városmajor Street 68, 1122 Budapest, Hungary.
Béla Péter MerkelyHeart and Vascular Centre of Semmelweis University, Városmajor Street 68, 1122 Budapest, Hungary.
Pál ÁbrahámHeart and Vascular Centre of Semmelweis University, Városmajor Street 68, 1122 Budapest, Hungary.ORCID https://orcid.org/0000-0001-5645-9855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the broadening spectrum of heart rhythm-monitoring techniques, the most appropriate modality and duration to detect atrial fibrillation (AF) are not consensual. Two-dimensional speckle tracking for left atrial strain analysis seems feasible to detect atrial cardiomyopathy, which represents a substrate for AF. We aimed to perform a systematic review and meta-analysis on peak atrial longitudinal strain (PALS) and contraction strain rate (pLAct) differences as primary outcomes measured in sinus rhythm (SR) between patients with and without future AF during follow-up (FU). Random-effect model was used. For continuous outcomes, we calculated weighted mean differences (WMD) to compare the two groups We identified eight eligible articles consisting of 1230 patients. Six articles were eligible for quantitative PALS analysis, while three were eligible regarding pLAct. The baseline parameters of the future AF and SR patients were comparable in most of the papers. The PALS value in patients developing future AF was significantly lower compared to patients with no AF (WMD: -5.55% 95% CI -7.06 to -4.03%). Pooled WMD of pLAct between the groups was -0.44 1/s, 95% CI: -0.56 to -0.33 1/s. Baseline PALS and pLAct values of future AF patients were significantly lower than those who remained in SR during FU. PALS and pLAct seem to be sensitive parameters which can be implemented in a predictive model for AF enabling us to find patients who need prolonged heart rhythm-monitoringand it can be also a guidance for oral anticoagulation indication setting.

Indexed as

Atrial cardiomyopathyAtrial fibrillationLeft atrial strainPALSSpeckle-tracking echocardiography

Identifiers

PMID40444217
PMCPMC12120665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.