ArticleFood science & nutrition2025
From Diet to Scar: Novel Mendelian Randomization and Mediation Analyses Linking Dietary Habits, Gut Microbiota, and Hypertrophic Scarring.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Developmental Programming of Drug Response: Microbiota as a Missing Dimension in Perinatal Drug Discovery.International journal of molecular sciences · 2026Review
- Gut microbiota-derived metabolites in keloid and hypertrophic scarring.Frontiers in microbiology · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertrophic scarring (HTS) is a pathological skin condition characterized by excessive collagen deposition during wound healing. Emerging evidence suggests that dietary habits and gut microbiota composition may influence HTS risk via systemic inflammatory and metabolic pathways. However, the causal relationships between these factors remain poorly understood. Mendelian randomization (MR) analysis was conducted to investigate the causal relationships between dietary habits, gut microbiota composition, and HTS risk. Additional analyses included mediation analysis to explore potential intermediary effects of gut microbiota and co-localization analysis to assess shared genetic loci between exposures and HTS. MR analysis identified significant associations between HTS and six dietary preferences, with caffeinated/sweet liking and jam liking increasing HTS risk, while crisps, curry, oranges, and strong flavor liking were protective. For gut microbiota,
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Registered trials
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