ArticleFrontiers in oncology2025
Impact of Hashimoto's thyroiditis on ultrasound diagnosis of papillary thyroid carcinoma: a retrospective study.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- The combination of virtual touch tissue imaging quantification (VTIQ) and American College of Radiology's Thyroid Imaging Reporting and Data System (ACR TI-RADS) improves the diagnostic efficiency for thyroid nodules with Hashimoto's thyroiditis: a retrospective study.Quantitative imaging in medicine and surgery · 2026Article
- Assessment of malignant risk in thyroid nodules classified as category 4 and above against a background of Hashimoto's thyroiditis.Gland surgery · 2026Article
- Nomogram combining clinical and ultrasonographic features for differentiating granulomatous lobular mastitis from invasive lobular carcinoma.Frontiers in oncology · 2026Article
- Analysis of ultrasound features and clinical manifestations of struma ovarii.Frontiers in oncology · 2026Article
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6 authors.
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Abstract
Objective: To investigate the clinical features and ultrasonic manifestations of papillary thyroid carcinoma (PTC) with Hashimoto's thyroiditis (HT) and without HT. The characteristics were analyzed to improve the accuracy of diagnosing PTC with HT via ultrasound, potentially reducing overtreatment in certain cases. Methods: The patients were retrospectively analyzed in the Second Hospital of Shandong University from December 2015 to January 2020. A total of 5732 patients had thyroid nodules on ultrasound. Among them, 553 patients (702 nodules) received surgical treatment and the histopathological results showed PTC with or without HT were enrolled. Univariate and multivariate analyses were conducted to evaluate the risk factors associated with HT influencing the ultrasound diagnosis of PTC. The nodules were categorized into two groups based on pathological results: PTC with HT and PTC without HT. Results: Gender, nodule echo, posterior echo change, border, aspect ratio, and nodule invasion rate significantly differed between the two groups ( Conclusions: HT can affect the clinical and ultrasonographic features of PTC in distinct ways. It provides a protective effect on the capsule, significantly reducing capsular invasion, while female gender and an aspect ratio ≥1 are associated with an increased risk of PTC with HT diagnosis.
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